The Acropolis of Athens is one of the most prestigious ancient monuments in the world, attracting daily many visitors, and therefore its structural integrity is of paramount importance. During the last decade an accelerographic array has been installed at the Archaeological Site, in order to monitor the seismic response of the Acropolis Hill and the dynamic behaviour of the monuments (including the Circuit Wall), while several optical fibre sensors have been attached at a middle-vertical section of the Wall. In this study, indicative real time recordings of strain and acceleration on the Wall and the Hill with the use of optical fibre sensors and accelerographs, respectively, are presented and discussed. The records aim to investigate the static and dynamic behaviour – distress of the Wall and the Acropolis Hill, taking also into account the prevailing geological conditions. The optical fibre technology, the location of the sensors, as well as the installation methodology applied is also presented. Emphasis is given to the application of real time instrumental monitoring which can be used as a valuable tool to predict potential structural risk.