Mentoring employees in healthcare institutions is essential: it helps to elicit enduring commitment in the delivery of efficient and effective medical services. This study aims at determining the effect of employee mentoring on sustainable commitment of workers towards achieving the goals of healthcare delivery. The research adopted a correlational survey design. For the purpose of this study, three university teaching hospitals in the south-south region of Nigeria were randomly selected. Purposive sampling was used to select 131 participants for the study. Primary data was collected through pretested structured questionnaire. The study reveals that employee mentoring has a strong impact on commitment of healthcare workers towards efficient service delivery. The study suggests the need for managers of healthcare personnel to attach more importance/interest to group/team, one-protégé-one mentor, and informal mentoring because it has been found to significantly contribute to overall workers commitment.