personalization oriented toward career management of secondary-school teachers loyalty in Cameroon. This study passed through two stages. Firstly, an exploratory qualitative study through an interview guide. This exploratory qualitative study permitted us to notice that teachers have a favorable opinion on having to choose their conditions of work in general and to list the axes of personalization customization that could be taken into account in teaching resources management. After that, the quantitative study was carried out, and data collection has been done through a questionnaire, on a sample of 414 secondary school teachers. These collected data were analyzed from the structural equation modeling. It shows that teachers express a demand to personalize their treatment. All this negatively affects their loyalty, in relation to their profession (organizational commitment and intention to quit). We therefore, suggest that the government of Cameroon should seek to personalize teaching staff management (in the matter of career and recruitment) to absorb perceived injustice and to boost loyalty.