Zika is a viral infection caused primarily by the bite of the Aedes aegypti mosquito. It is asymptomatic and may present: fever, headache, myalgia, arthralgia, asthenia and maculopapular rash. Neurological or autoimmune complications. Objective: To analyze the behavior of the Zika virus and its association with risk factors in the population of Herrera. Methodology: Retrospective cross-sectional prevalence study, using the digitalized mandatory notification form of the Surveillance System and the report on the presence of breeding sites from the MINSA vector department. A database was developed in the Excel program and inferential analysis in epiinfo.