Pemphigus vulgaris (PV) is a debilitating autoimmune disease that seems to have genetic predilection. In most cases it appears to affect mainly oral mucosa but can also occur in conjunction with skin lesions affecting different areas of the body. Oral involvement is characterized by the presence of erosions whereas skin lesions are mainly flaccid bulla (early) or erosions (late). PV is characterized by the formation of extremely fragile bulla that frequently rupture forming denuded, painful, easily bleeding erosions that often become crusted.