global-journal-of-medical-research-b-pharma-drug-discovery-toxicology-medicine Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine 0975-5888 2249-4618 Global Journals Publishing Group Incorporated 59844 Formulation of an Antidiabetic Herbal Capsule from Isolated Compounds of Ethanolic Extract of Dregea Volubilis and Leptadenia Reticulata NatarajanVenkatesan Anton Smith. B.AVishwanath. DSuchitra. INDIA 15 07 2021 21 B2 37 45

The present investigation was aimed to formulate capsule formulations containing isolated compounds from Dregea volubilis and Leptadenia reticulata. In order to obtain anti diabetic formulations with more effective oral hypoglycemic activity, less side effects, increased patient compliance thereby providing multifaceted benefits. DVLR (DV and LR isolated fraction was mixed in 1:1 ratio) capsules were formulated and the study was carried out for its antidiabetic effect of STZ and HFD induced diabetic rats. Preformulation of capsules were observed as angle of repose and bulk density. Finished capsule formulations were evaluated for weight variation, pH, moisture content, disintegration time, in vitro-drug release percentage and in vivo anti diabetic studies. In our study showed empty capsule shell pH was observed as 3.62 and moisture content of capsule was found as

 diabetes mellitus polyphenolic compound herbal form ulation. Full Text

The present investigation was aimed to formulate capsule formulations containing isolated compounds from Dregea volubilis and Leptadenia reticulata. In order to obtain anti diabetic formulations with more effective oral hypoglycemic activity, less side effects, increased patient compliance thereby providing multifaceted benefits. DVLR (DV and LR isolated fraction was mixed in 1:1 ratio) capsules were formulated and the study was carried out for its antidiabetic effect of STZ and HFD induced diabetic rats. Preformulation of capsules were observed as angle of repose and bulk density. Finished capsule formulations were evaluated for weight variation, pH, moisture content, disintegration time, in vitro-drug release percentage and in vivo anti diabetic studies. In our study showed empty capsule shell pH was observed as 3.62 and moisture content of capsule was found as