Background: Wound is the disruption of cellular and anatomic continuity of living tissue produced by physical, chemical, electrical or microbial insults to the tissue. Wound healing is the dynamic process of regeneration or repair of broken tissue, due to increasing health care costs, an ageing population, and a sharp rise in the incidence of diseases such as diabetes and obesity worldwide, the present study was aimed to achieve the following objectives. Objectives: This study aimed to determine the effect of African panaxia on bacteria wound infection. Methods: It was a Laboratory based experimental study made up of bacterial isolates from wounds, cultured on blood, EMB agar, followed by confirmatory biochemical tests and MI and MBC was done turbidity absorbance measured using spectrophotometry at 660nm. Data was analyzed using Microsoft excel 2010.