Blastomycosis or "Gilchrist disease" is a deep mycosis due to a dimorphic fungus: "Blastomyces Dermatitidis." It is a telluric fungus of the wooded areas of the Eastern North American continent, causing chronic granulomatous diseases, responsible for pulmonary manifestations due to the inhalation of its spores. Dissemination can lead to skin, bone, visceral, and even neurological signs that can be fatal. We report the case of a 50-year-old African man who has been complaining for five days before admission of headaches and behavioral disorders