This paper examined the current issues and challenges facing the acquisition of OTME skills in Federal College of Education (Technical), Asaba. Office Technology and Management is a synergy of three distinct words office, technology and management. It is a well-established fact that advances in technology has affected different professions with a view to meet global trends in higher productivity, speed networking and excellent packaging. Accomplishing the routine tasks with machines is known as automation. To this end, this paper examines inter alia the concept of office technology and management, the concept of skills, importance of acquiring OTME Skills in Nigeria skills available in OTME, and issues and challenges in the acquisition of OTME skills. This paper concludes that no meaningful OTME skill can be acquired in colleges of education without adequate provision of facilities, manpower and equipment needed in OTME departments to meet the changing needs of the society and workplace.