The prime focus of the study is to explain what to do about climate change-caused flooding and the associated diseases in Rivers State of Nigeria. In doing so, this work gives an overview of climate change-caused flooding and effects of flooding on people in flooded areas, as well as explains flooding associated diseases in Rivers State. Besides this, it further proffers legislative, short-term and long-term measures that will help reduce if not eliminate flooding and its associated diseases in Rivers State of today, and indeed of the future.