global-journal-of-science-frontier-research-b-chemistry Global Journal of Science Frontier Research - B: Chemistry 0975-5896 2249-4626 Global Journals Publishing Group Incorporated 75557 Antagonist Effect of Theophylline and Caffeine on Some Transaminase Enzymes Activities AbbassDr. Salma Abdul Rudha IRAQ, AL-Mustansiriyah university, college of science, department of chemistry 25 02 2013 13 B3 29 27

The purpose of this study is to show the effect of caffeine and theophylline on the activities of aspartate aminotransferase AST and alanine aminotransferase ALT, in the human sera. Serum AST and ALT were activated by caffeine, while inhibiting by theophylline, this effect increased with increasing the concentration of theophylline and caffeine. Kinetic properties of AST and ALT activities revealed by theophylline and that non-competitive inhibition type, and non-competitive activation by caffeine.

 thophylline aminotransderase caffeine kinetic Full Text

The purpose of this study is to show the effect of caffeine and theophylline on the activities of aspartate aminotransferase AST and alanine aminotransferase ALT, in the human sera. Serum AST and ALT were activated by caffeine, while inhibiting by theophylline, this effect increased with increasing the concentration of theophylline and caffeine. Kinetic properties of AST and ALT activities revealed by theophylline and that non-competitive inhibition type, and non-competitive activation by caffeine.