global-journal-of-medical-research-b-pharma-drug-discovery-toxicology-medicine Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine 0975-5888 2249-4618 Global Journals Publishing Group Incorporated 76221 Effect of Oral Administration of Chloramphenicol on Hematological Profile of Male Charles Foster Rats ShuklaP. SinghR. K. INDIA, CSIR- Central Drug Research Institute, Lucknow 15 01 2013 13 B4 17 21

For a given organism, relevant information about the internal environment can be easily accessed by its hematological profile. Chloramphenicol being a potent broad spectrum antibiotic is used readily in eyed drop formulations and is also in food industry. In the present study, varying doses (750, 1500 and 2250 mg/kg B.Wt) of Chloramphenicol (CAP) was administered orally as single daily dosage for 24 days to Male Charles Foster rats, to assess the hematological changes associated with oral exposure to the drug. The results showed a significant (p

 CAP hematotoxicity blood cells CF rats. Full Text

For a given organism, relevant information about the internal environment can be easily accessed by its hematological profile. Chloramphenicol being a potent broad spectrum antibiotic is used readily in eyed drop formulations and is also in food industry. In the present study, varying doses (750, 1500 and 2250 mg/kg B.Wt) of Chloramphenicol (CAP) was administered orally as single daily dosage for 24 days to Male Charles Foster rats, to assess the hematological changes associated with oral exposure to the drug. The results showed a significant (p