Introduction: The operation of coronary shunting in patients with coronary heart disease leads to the development of various complications in the postoperative period, the most frequent are heart rhythm disturbances. Purpose: To establish the connection of intraoperative hemolysis (IOH) with the development of cardiac rhythm disturbances in patients with coronary artery disease after coronary shunting in conditions of cardiopulmonary bypass (CB). Material and Research Methods: The assessment of the degree of IOH was made by the level of free hemoglobin [Hb] in the blood plasma at the beginning of the operation, immediately after the patient was connected to the CB device and 15 minutes before removal from the CB, using the Hemo Cue Plasma / Low Hb analyzer. According to the degree of IOH, patients (n = 123) are divided into 3 groups (gr.) in accordance with free [Hb]: gr.1 – ≤0,1 g/l; gr.2 > 0.1 g/l and