A Randomised Controlled Study of Intramuscular Camylofin Dihydrochloride vs Intravenous Hyoscine Butylbromide in Augmentation of Labour

Dr Sunil S.Patil; Dr Shridhar S. Dayama; Dr Pradip W. Sambarey

A Randomised Controlled Study of Intramuscular Camylofin Dihydrochloride vs Intravenous Hyoscine Butylbromide in Augmentation of Labour

Dr Sunil S.Patil * §

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Dr Shridhar S. Dayama

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Dr Pradip W. Sambarey

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B.J.Govt.Medical College and Sassoon Hospital, Pune,...

A Randomised Controlled Study of Intramuscular Camylofin Dihydrochloride vs Intravenous Hyoscine Butylbromide in Augmentation of Labour

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Abstract

Aims and objectives-to study and compare the effectiveness of injection Camylofin and injection Hyoscine in accelerating active phase of the 1st stage of labour in uncomplicated pregnancies. Second was to study the effects of the two drugs on 2nd and 3rd stage of labour and to study the adverse drug reactions on the mother and fetus. Method-This was randomized controlled prospective study.150 Primigravida in the age group 18 to 30 years with gestational age 37 to 40 weeks were included. The cases were divided into 3 groups Group I consisted 50 women which was Control Group. Group II consisted of 50 women who were given injection Camylofin intramuscular. Group III consisted of 50 women who were given injection Hyoscine intravenous. Result-There was significant reduction in duration of active phase of labour and improvement in the rate of cervical dilatation with Camylofin compared to Hyoscine butylbromide. There were no maternal, fetal side effects associated to these drugs.

References

6 Cites in Article

Reference Format

G Liggins (1978). Ripening of the cervix.
Phyllis Leppert (1995). Anatomy and physiology of cervical ripening.
H Warke,A Chauhan,V Raut,K Ingle (2003). Efficacy of camylofin dihydrochloride in acceleration of labour: A randomised double blind trial.
S Kaur,S Bajwa,P Kaur,Bhupals (2013). To compare the effect of Camylofin dihydrochloride (Anafortan) with combination of Valethamate Bromide (Epidosin) and Hyoscine Butyl bromide (Buscopan) on cervical dilatation.
K Singh,P Jain,N Goel (2004). Drotaverine Hydrochloride for augmentation of labour.
K Tiwari,R Jabeen,N Sabzposh,J Rabbani (2003). Comparison of Hyoscine N -butyl bromide and Valethamate bromide in shortening the duration of labour.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Dr Sunil S.Patil, Dr Shridhar S. Dayama, Dr Pradip W. Sambarey. 2016. "A Randomised Controlled Study of Intramuscular Camylofin Dihydrochloride vs Intravenous Hyoscine Butylbromide in Augmentation of Labour". Global Journal of Medical Research - E: Gynecology & Obstetrics GJMR-E Volume 16 (GJMR Volume 16 Issue E1).

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GJMR Volume 16 Issue E1

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Journal Specifications

Crossref Journal DOI 10.17406/gjmr

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

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Classification

GJMR-E Classification NLMC Code: WJ 190

Submission ReceivedDecember 11, 2015
Peer Review Double Blind
Handling Editor
Accepted January 3, 2016
Published January 15, 2016

Version of record

v1.2

Issue date

May 3, 2016

Language

English

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Article Matrices

Total Score: 143

Country: India

Subject: Global Journal of Medical Research

Authors: Dr Shridhar S. Dayama, Dr Sunil S.Patil, Dr Pradip W. Sambarey (PhD/Dr. count: 0)

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Publish Date: 2016 01, Fri

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Total Views: 1.8K

Total Downloads: 122

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