Clove (Eugenia Caryophyllata) Extraction and Synthesis of New Pyrazole Derivatives from Eugenol

Clove (Eugenia Caryophyllata) Extraction and Synthesis of New Pyrazole Derivatives from Eugenol

M. Khouili

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S. Hamri

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K. Rhazri

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A. Hafid

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H. Ouchetto

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Y.Hajbi

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Université Sultan Moulay Slimane

Clove (Eugenia Caryophyllata) Extraction and Synthesis of New Pyrazole Derivatives from Eugenol

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Abstract

An efficient method for the preparation of novel 1,3,4-trisubstituted 4,5-dihydro-1H- pyrazoles via 1,3-dipolar cycloaddition has been described. Using this method, various pyrazole were synthesized from eugenol, a major phenolic constituent of clove bud essential oil, as dipolarophilic system and N-aryl-C-ethoxycarbonitrilimine: the (Z)-ethyl 2-bromo-2-(2-(4chlorophenyl)-hydrazono) acetate.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

M. Khouili. 2013. \u201cClove (Eugenia Caryophyllata) Extraction and Synthesis of New Pyrazole Derivatives from Eugenol\u201d. Global Journal of Science Frontier Research - B: Chemistry GJSFR-B Volume 13 (GJSFR Volume 13 Issue B7).

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GJSFR Volume 13 Issue B7

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Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords

1 3-dipolar cycloaddition clove (eugenia caryophyllata)dipolarophile eugenol nucleo-philic substitution (SN)pyrazole

Submission ReceivedAugust 11, 2013
Peer Review Double Blind
Handling Editor
Accepted August 31, 2013
Published September 12, 2013

Version of record

v1.2

Issue date

December 25, 2013

Language

English

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Article Matrices

Total Score: 126

Country: Morocco

Subject: Global Journal of Science Frontier Research - B: Chemistry

Authors: S. Hamri, K. Rhazri, A. Hafid, H. Ouchetto, Y.Hajbi, M. Khouili (PhD/Dr. count: 0)

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Total Downloads: 2385

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