Efficacy Of Halofantrine In Mice Infected With Plasmodium berghei

Dr. Ologunde

Efficacy Of Halofantrine In Mice Infected With Plasmodium berghei

Dr. Ologunde * §

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§ The Federal Polytechnic, Ado-Ekiti.

Efficacy Of Halofantrine In Mice Infected With Plasmodium berghei

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Abstract

Drug adulteration is commonly reported in Nigeria. Halofantrine purchased in four different locations in Ondo and Ekiti state, Nigeria were tested in mice for their comparative efficacy. The average parasite clearance time (PCT) were 4.4±0.49, 4.2±0.40, 4.4±0.80 and 4.2±0.75 for Halofantrine coded HAL-AK, HAL-IO, HAL-AD and HAL-IK respectively. Also, average parasite clearance rate (PCR) were 8653±2557, 6895±1010, 5426±1850 and 6226±1850 respectively. The result shows that there was no significant difference in the PCR (P>0.05) between the drugs. All the halofantrine drugscompletely cleared the parasites within 4-5 days. The results of this study indicates that adulteration of Halofantrine is not presently in circulation in areas of Ondo and Ekiti states, South Western Nigeria.

References

9 Cites in Article

Reference Format

O Aina,P Emeka,A Akintonwa,P Agomo,O Aina (2006). Comparative efficacy of dihydroartemisinin, chloroquine and combination of dihydroartemisinin and chloroquine or mefloquine in mice infected with <i>Plasmodium berghei</i>.
J Breman (2001). The ears of hippopotamus manifestation determinants and estimates of the malaria burden.
C Lon,R Tsuyuoka,S Phanouvong (2006). Counterfeit and substandard antimalaria drugs in Cambodium.
C Ologunde,A Akinyemi,D Fagbohun,V Ajibade (2004). A statistical study of some blood films requests in some health center in four southern states of Nigeria for malaria.
C Ologunde,A Akinlalu (2007). Agricultural Performance of Irepodun/Ifelodun Local Government Area in Ekiti State: Implications for Health Challenges.
Osaloni Bankole Ojo,Israel Akinadewo,Simeon Duduyegbe,Julius Fasakin Akinola,Owoeye Taiwo Omolade (2008). AI-driven decision-making in financial management.
Robert Snow,Carlos Guerra,Abdisalan Noor,Hla Myint,Simon Hay (2005). The global distribution of clinical episodes of Plasmodium falciparum malaria.
Halidou Tinto,Claude Rwagacondo,Corinne Karema,Denise Mupfasoni,Waltruda Vandoren,Emmanuel Rusanganwa,Annette Erhart,Chantal Van Overmeir,Eric Van Marck,Umberto D’alessandro (2006). In-vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, dihydroartemisinin and quinine in an area of high chloroquine resistance in Rwanda.
N White (2004). Antimalaria drug resistance.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Dr. Ologunde. 2012. "Efficacy Of Halofantrine In Mice Infected With Plasmodium berghei". Global Journal of Medical Research - F: Diseases GJMR-F Volume 12 (GJMR Volume 12 Issue F3).

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GJMR Volume 12 Issue F3

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Journal Specifications

Crossref Journal DOI 10.17406/gjmr

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

Adulteration clearance rate halofantrine parasite clearance

Classification

GJMR-F Classification NLMC Code: QX 135

WC 405

Submission ReceivedDecember 6, 2011
Peer Review Double Blind
Handling Editor
Accepted January 4, 2012
Published January 15, 2012

Version of record

v1.2

Issue date

May 7, 2012

Language

English

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Article Matrices

Total Score: 153

Country: Nigeria

Subject: Global Journal of Medical Research

Authors: Dr. Ologunde, C. A., Olaoye, A. B., Olofinjana, O., Akogun, O. O. (PhD/Dr. count: 1)

View Count (all-time): 330

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Publish Date: 2012 01, Sun

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Total Views: 2.2K

Total Downloads: 151

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