Evaluation of Methanolic Extract of Hypericum Mysorense Ointment for its Wound Healing Activity

Dr.C.Sankar; Muthukumar S; Arulkumaran G; Vinesha R; Senthilkumar P; Sandeep George Simson

Evaluation of Methanolic Extract of Hypericum Mysorense Ointment for its Wound Healing Activity

Dr.C.Sankar * §

Contact

Sandeep George Simson

Contact

§ KMCH college of Pharmacy

Evaluation of Methanolic Extract of Hypericum Mysorense Ointment for its Wound Healing Activity

Article Fingerprint

ReserarchID

MRY9A32

Evaluation of Methanolic Extract of Hypericum Mysorense Ointment for its Wound Healing Activity Banner

AI TAKEAWAY

Connecting with the Eternal Ground

Abstract

The main objective of the present study is to formulate and evaluate semi-solid dosage forms of Hypericum mysorense for its wound healing activity. The stem of Hypericummysorense was extracted by continuous hot percolation/ soxhletationusing methanol as solvent and was evaluated for its phytochemical property, in-vitro antimicrobial andin-vitro antioxidant activity. Using this methanolic extract, semi-solid dosage form(ointment) was formulated. Ointment was prepared using 2% concentration of the extract by fusion method using emulsifying ointment. Hence, the ointment containing 2% methanolic extract of Hypericummy-sorense was evaluated for its wound healing activity using excision wound model. The effect produced by the extract ointment, in terms of wound contracting ability, wound closure time and histopathological characteristics were comparable to that of a standard drug povidone iodine ointment. Therefore, the present study concluded that the Hypericum mysorense at 2% concentration of the methanolic extract formulated as an ointment showed a better wound healing formulation for better patient care and pharmaco economical.

References

16 Cites in Article

Reference Format

Yogesh Sharma,G (2013). Jeyabalan and Ramandeep Singh: Current Aspect of Wound Healing Agents From Medicinal Plants. A Review.
V Meher-Homji (1967). Phytogeography of the South Indian Hill Stations.
Laurence Harwood,Christopher (1999). Moody: Experimental organic chemistry.
Mohammed Dr,Ali (1998). Textbook of Pharmacognosy.
K M Dr,Nadakarni (2002). Indian Meteria Medica.
P Warrier (1996). Indian medicinal plants.
K Pulok,Mukherjee (2002). Quality control of Herbal Drugs(An approach to Evaluation of Botanicals).
Dr,C Kokate (2004). Polynomial Kalman Filters.
Sundarrajan (1998). Unknown Title.
Simmi Ratan,Anju Gambhir,S Mullick,John Ratan (2000). Lipoblastoma of the neck.
A Almagboul,A Bashir,Farouk,A Salih (1985). Antimicrobial activity of certain Sudanese plants used in folkloric medicine. Screening of antibacterial activity.
Raghu Chantrashekhar,H (2009). Antioxidant activity of Hypericumhookerianum.
R Roberta (1999). Antioxidant activity applying an improved ABTS radical cation decolourization assay.
Uma Shankar Mishra,P Murthy,Debananda Mishra,Charana Kanhu,Sahu (2011). Formulation and Standardisation of herbal gel containing methanolic extract of Calophyllum inophyllum.
S Barhate,K Bavaskar,Y Saoji,M Potdar,T Gholap (2009). Development of Transdermal drug delivery system of Ketoprofen.
Purnima Kumari,Poonam Yadav,Rani Priya,Sandeep Verma1,Arvind Kumar,A Arya (2013). Review on wound healing properties of Indian medicinal plants.

Download References

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Senthilkumar P, Sandeep George Simson. 2020. "Evaluation of Methanolic Extract of Hypericum Mysorense Ointment for its Wound Healing Activity". Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 20 (GJMR Volume 20 Issue B1).

More Citation Formats

Select Citation Style:

Download Citation

GJMR Volume 20 Issue B1

Explore Journals Explore Volume Read This Issue

Journal Specifications

Crossref Journal DOI 10.17406/gjmr

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

Not Found

Classification

GJMR-B Classification NLMC Code: QV 55

Submission ReceivedDecember 8, 2019
Peer Review Double Blind
Handling Editor
Accepted January 1, 2020
Published January 15, 2020

Version of record

v1.2

Issue date

February 22, 2020

Language

English

Experiance in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

View in VR

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

View in 3D

Article Matrices

Total Views: 913

Total Downloads: 45

All Trends