High-Flow Priapism Following Chlorpromazine Induced Low- Flow Priapism

Mohamed Saad Hegazy; Mustafa MR

High-Flow Priapism Following Chlorpromazine Induced Low- Flow Priapism

Mohamed Saad Hegazy * §

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Mustafa MR

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§ Vice Dean Armed Forces College of Medicine Cairo

High-Flow Priapism Following Chlorpromazine Induced Low- Flow Priapism

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Abstract

Priapism is defined as a penile erection that persists more 4 hours or longer and is unrelated to sexual activity. The three main subtypes are low flow (ischemic), high flow (nonischemic) and stuttering (intermittent or recurrent) priapism. Alpha-1 antagonistic activities of some antipsychotics, especially chlorpromazine, have been reported to be responsible for development of low-flow priapism. Chlorpromazine has the greatest alpha-adrenergic affinity among the conventional antipsychotic agents and the most frequently reported to be associated with priapism. We report a case of priapism after a first single dose of chlorpromazine (Neurazine ® 100 mg tablet, Misr Co. For Phramind-Egypt). The case was presented first by neglected lowflow priapism that had been converted to high-flow priapism due to injury of a branch of the cavernosal artery, during aspiration and irrigation treatment procedure, proved by blood gas testing of the aspirated penile blood, penile color duplex Doppler ultrasonography and selective left internal pudendal arteriogram. This conversion is an uncommon complication of such procedure.

References

14 Cites in Article

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Mohamed Saad Hegazy, Mustafa MR. 2018. "High-Flow Priapism Following Chlorpromazine Induced Low- Flow Priapism". Global Journal of Medical Research - K: Interdisciplinary GJMR-K Volume 18 (GJMR Volume 18 Issue K5).

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GJMR Volume 18 Issue K5

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Journal Specifications

Crossref Journal DOI 10.17406/gjmr

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

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Classification

GJMR-K Classification NLMC Code: WK 900

Submission ReceivedDecember 15, 2017
Peer Review Double Blind
Handling Editor
Accepted January 1, 2018
Published January 15, 2018

Version of record

v1.2

Issue date

September 14, 2018

Language

English

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Article Matrices

Total Score: 143

Country: Egypt

Subject: Global Journal of Medical Research

Authors: Mohamed Saad Hegazy, Mustafa MR, Mustafa MR (PhD/Dr. count: 0)

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Publish Date: 2018 01, Mon

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