Molecular Epidemiology of Bovine Tuberculosis in Cattle and its Public Health Implications in Gambella Town and its Surroundings, Gambella Regional State, Ethiopia

Jemberu Alemu
Jemberu Alemu * §
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Gezahegne Mamo
Gezahegne Mamo
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Gobena Ameni
Gobena Ameni
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§ Gambella University, Ethiopia

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Molecular Epidemiology of Bovine Tuberculosis in Cattle and its Public Health Implications in Gambella Town and its Surroundings, Gambella Regional State, Ethiopia

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Abstract

A cross sectional study was conducted from December 2014 to May 2015 in Gambella town municipal abattoir and health centers to investigate the prevalence of BTB, isolation and molecular characterization of its causative agents and to assess its public health implications in Gambella, Ethiopia. Postmortem examination, bacteriological culturing, RD deletion typing and spoligotyping were used for investigation. The overall prevalence of BTB in cattle was 13.2% (66/500) on the basis of detailed postmortem examination. Statistical significant difference was observed in the prevalence of BTB among different body conditioned animals (χ2 = 39.105, P=0.000and breeds (χ2 = 24.996, P=0.000). Molecular characterization of 11 mycobacterial isolates from human patients using RD9 deletion typing showed that all were M. tuberculosis and further spoligotyping of the isolated revealed that SIT289, SIT134, SIT1634, SIT142 and one new strain not found in the spoligotype databases.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

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How to Cite This Article

Jemberu Alemu, Gezahegne Mamo, Gobena Ameni. 2016. "Molecular Epidemiology of Bovine Tuberculosis in Cattle and its Public Health Implications in Gambella Town and its Surroundings, Gambella Regional State, Ethiopia". Global Journal of Medical Research - F: Diseases GJMR-F Volume 15 (GJMR Volume 15 Issue F5).

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Journal Specifications

Crossref Journal DOI 10.17406/gjmr

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-F Classification NLMC Code: WF 200
  • Submission ReceivedApril 11, 2015
  • Peer Review Double Blind
    Handling Editor
  • Accepted April 30, 2015
  • Published May 15, 2015
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v1.2

Issue date
January 6, 2016

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English
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Molecular Epidemiology of Bovine Tuberculosis in Cattle and its Public Health Implications in Gambella Town and its Surroundings, Gambella Regional State, Ethiopia

Jemberu Alemu
Jemberu Alemu Gambella University, Ethiopia
Gezahegne Mamo
Gezahegne Mamo
Gobena Ameni
Gobena Ameni
  • Submission ReceivedApril 11, 2015
  • Peer Review Double Blind
    Handling Editor
  • Accepted April 30, 2015
  • Published May 15, 2015