Synthesis of 1-(2-(4-Substitutedphenylamino)-Imidazo[2,1-B] Benzothiazole-3-Yl) Propan-1-One

Chalak Azimi

Synthesis of 1-(2-(4-Substitutedphenylamino)-Imidazo[2,1-B] Benzothiazole-3-Yl) Propan-1-One

Chalak Azimi * §

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§ Department of Chemistry Management, College of Chemi...

Synthesis of 1-(2-(4-Substitutedphenylamino)-Imidazo[2,1-B] Benzothiazole-3-Yl) Propan-1-One

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Abstract

4-propionyl-3-(4-substitutedphenylamino) isoxazol-5(2H)-one, substituted on nitrogen with a 2-chlorobenzot-hiazole group, reacts with triethylamine (TEA) in ethanol under reflux conditions to provide a convenient synthesis of 1-(2-(4-substitutedphenyl amino) -imidazo [2,1b] benzothiazole-3-yl) propan-1-one.

References

33 Cites in Article

Reference Format

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(2-(4-bromophenylamino)-imidazo[2,1-b] benzothiazole-3-yl) propan-1-one (15, X.
mmol) and triethylamine (0.3 mL) were refluxed in ethanol (10 mL) for 24 hours. The reaction mixture was left to cool to room tempreture and resulting precipitate was colleted to afford 1-(2-(4-bromophenylamino)imidazo [2, 1-b] benzothiazole-3-yl) propan-1-one as white needles.
(null). Figure 2—figure supplement 1. 1H and 13C NMR spectra of compound 3..
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(J=8.). Unknown Title.
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(null). Figure 2—figure supplement 1. 1H and 13C NMR spectra of compound 3..
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mmol) and triethylamine (0.3 mL) were refluxed in ethanol (10 mL) for 24 hours. The reaction mixture was left to cool to room tempreture and resulting precipitate was colleted to afford 1-(2-(4-nitrophenylamino)-imidazo.
C (null). Enhanced Method for the Synthesis and Comprehensive Characterization of 1(4-Phenylquinolin-2-yl)propan-1-one.
6 -DMSO)(δppm): 1.18.
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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Chalak Azimi. 2014. "Synthesis of 1-(2-(4-Substitutedphenylamino)-Imidazo[2,1-B] Benzothiazole-3-Yl) Propan-1-One". Global Journal of Science Frontier Research - B: Chemistry GJSFR-B Volume 14 (GJSFR Volume 14 Issue B2).

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GJSFR Volume 14 Issue B2

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Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords

2-chlorobenzothiazole imidazobenzothiazoles isoxazolones triethylamine (tea)

Classification

GJSFR-B Classification FOR Code: 250301

030599

Submission ReceivedApril 1, 2014
Peer Review Double Blind
Handling Editor
Accepted April 21, 2014
Published May 4, 2014

Version of record

v1.2

Issue date

May 28, 2014

Language

English

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Article Matrices

Total Score: 127

Country: Iran

Subject: Global Journal of Science Frontier Research

Authors: Chalak Azimi, Helal Tahazadeh, Rasol Kamari (PhD/Dr. count: 0)

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