## I. INTRODUCTION
The unconscious struggle of a person with pathogenic viruses began, one might say, back in the cave age. And it began with the use of fire, which not only allowed to warm up, but also cleansed the air of viruses, including air with infrared radiation [1]. And the conscious struggle against viruses and bacteria began by trial and error, which our ancestors made for many centuries. And this conscious struggle resulted in empirical recipes for traditional medicine. With the development of science, the possibilities of influencing both identified viruses and humans have expanded. Due to the increase in the effectiveness of impacts, the time for accumulating positive results has been reduced. BUT! But at a very high price - they try not to advertise, but also to quickly obtain predominantly negative results. And this empirical method of finding positive influences continues to this day.
Now more than 6 thousand types of viruses have been described in sufficient detail [2]. Although some researchers suggest that there are more than a hundred million of them [3]. Viruses are found in almost every ecosystem on Earth [4]. They are the most numerous biological form [5]. The study of viruses is an independent science of virology, a section of microbiology. But even she, with a purely empirical approach, according to the above data, has not mastered even one ten thousandth of the estimated number of viruses and, in fact, does not yet have a strict and sufficiently complete phenomenology. And for lack of a better one, the bureaucratic medical machine uses it, based, in fact, only on such meager knowledge, recommendations. Uses as the most reliable?! Taking into account the UNSTUDY proto-viruses, the situation looks even worse. And the purely empirical accumulation of data on consequences-diseases continues. And, as the pandemic showed, virology actually ended up at the tail end of its development. So much in the tail that decisions on mass treatments were made not at all by virologists, but by clerks, starting from the highest level and ending with the lowest. But even without a pandemic, there is a high probability that many common genetic diseases are determined by UNCOVERED and unidentified viruses and protoviruses.
Obviously, without FINDING and ACCOUNTING exactly the Fundamental Laws of the "Sea of Viruses", the CAUSES and many diseases, and the occurrence of pandemics cannot be found. And humanity will continue to swim in this "sea" at the behest of the waves, as in the cave age, consciously reacting only to a tiny part of pathogenic influences.
The fundamental approach with the awareness (Theory) of Infinite Sets (Viruses) and the presence of viral INVARIANTS in them, and using the methodological achievements of related sciences in Virology, will make it possible to break away from bare empiricism and build Fundamental Virology. And this is what will provide mankind with a "higher sense" in identifying viral Problems and in finding ways to solve them. And the fact that the virus problem is coming was shown half a century ago in his works carried out in the Antarctic expedition, my friend, Doctor of Biological Sciences Vyacheslav Krylenkov - his results demonstrated an exponential increase in the concentration of biomass in the air. And the exhibitor is a harbinger of disaster.
## II. PHENOMENOLOGICAL ASPECTS OF THE EMERGENCE OF VIRUSES
The first phenomenological aspect is the "Game LIFE" [6] founded by the English mathematician John Conway in 1970, which is based on Statistics with the Accumulation of Information, which catastrophically reduces the TIME of the purely Statistical Occurrence of LIFE and removes the prohibition itself within the framework of traditional thermodynamics, on ITS Occurrence over time. the existence of the universe. This "GAME" has, in principle, the beginning at the most elementary, molecular level and, as follows from the works of Sergei Kozeev - on the cosmic "sperm" fullerenes. It is customary to tie viruses to the other end of the NON-LIVING-LIVING Nature range, to LIFE already formed at the cellular level. Thus, in principle, the "living" particles of Conway-von Neumann, which are not yet fragments of cells, but are their building material, are excluded from consideration. But even this limited approach made it possible to clarify the "Game of LIFE" itself, which considers the development of "LIFE" regardless of the properties of the development environment. In principle, taking into account the properties of the environment gives a variety of different forms of life. And this is what manifests itself and is observed by us precisely at the lowest level available to us - at the viral level, in the form of the presence of their "bricks". More complex forms of LIFE are clearly limited by the halo of "Habitat". So the Living Cell is the habitat of viruses, but the "bricks" of viruses are present in it with necessity.
The second - genealogically related to the first aspect, is the specific chemical thermodynamics of the "living" environment, which manifests itself in endothermic chemical reactions that occur during the development and reproduction of LIFE. Like primitive "bricks" - fullerenes, such a macroscopic proto-living medium is the polymeric state of matter. It is in the polymer environment that one should look for the next stage in the selection of the "Habitat of LIFE" [7, 8, 9].
And the third fundamentally important, but practically not taken into account yet, is the Dynamic ELEMENT OF LIFE - LIFE NOTES, reliably registered even on a separate Living Cell [10, 11]. Roughly speaking, by influencing a dead polymer with Mozart's Music, we can provoke the emergence of both Elementary "bricks" of viruses in it, and already quite large fragments of a Living Cell. As well as vice versa, by influencing HER on a Living Cell, we can destroy viruses in it that have turned off the Road of LIFE - disharmonious with it.
## III. STRUCTURE
Fragmented viral phenomenology naturally exists. Thus, it is described that while the virus is outside its range - in the extracellular environment or in the process of infecting a cell, it exists as an independent particle. Virus particles (virions) are known, which consist of two or three components: genetic material in the form of DNA or RNA (some, such as mimiviruses, have both types of molecules); a protein shell (capsid) that protects these molecules, and, in some cases, additional lipid shells. The presence of a capsid distinguishes viruses from virus-like infectious nucleic acids called viroids. Depending on the type of nucleic acid represented by the genetic material, DNA-containing viruses and RNA-containing viruses are isolated.
But, in isolation from the above aspects, it does not give a strict and complete, correct description of the nature of viruses. So their structural characterization does not even take into account the fact that not fragments of LIFE, but fragments of the ashes of LIFE were observed experimentally, which apparently makes it ambiguous whether viruses are classified as living or inanimate objects. After all, the "ashes" of viruses only make it possible to say that fragments of large specific
DNA or RNA molecules are present, but it does not even allow them to be systematized - whether the completed DNA/RNA is evidence of the completion of the "growth" of an individual virus.
After all, starting from the first results of DNA measurements, the biologists working in the Brega laboratory did not understand that the results of Bragg scattering, strictly speaking, are applicable only to DEAD physical objects, and even then only to those that correspond to the adiabatic expansion in order of low energy. The use of X-ray and electron-microscopic techniques does not even give the structure of a living particle, but the structure of the ash remaining from it. Not to mention that the Dynamic Element of Life is completely destroyed and thus drops out of the results of experiments.
Viruses show a huge variety of shapes and sizes. As a rule, viruses are much smaller than bacteria. Most of the studied viruses have a diameter ranging from 20 to $300\mathrm{nm}$. Some filoviruses are up to $1400\mathrm{nm}$ long, but only $80\mathrm{nm}$ in diameter. In 2013, Pandoravirus was considered the largest known virus, measuring $1 \times 0.5\mu \mathrm{m}$, but in 2014, Pithovirus was described from permafrost from Siberia, reaching $1.5\mu \mathrm{m}$ in length and $0.5\mu \mathrm{m}$ in diameter. It is currently considered the largest known virus.
The very fact of the existence of a micron virus necessarily raises the question of its growth and the possibility of classifying it as a virus at intermediate stages of its growth. But, in principle, these questions naturally apply to viruses of any size. And, as we see, there is not even a purely structural characterization of the difference between virus fragments and a complete virus.
Moreover, the fragmentary description of viruses used does not take into account the contribution of the Dynamic Element of LIFE. Whereas modern IR spectroscopy (in a sparing mode) and neutron scattering (during the destruction of a virus-like NANO-object) make it possible to identify not only the structure (Stradivarius violin), but the vibrations of atoms allowed for LIFE (NOTES of this violin).
## IV. GAPS AND FUNDAMENTAL QUESTIONS OF VIROLOGY
As can be seen from the initial cumulative phenomenology of viruses, despite numerous scattered data on (known) viruses, there are large gaps in their understanding, which leads to a number of fundamental questions.
Viruses are traditionally viewed as a Life Form. And the fact that they added the clause - NON-LIVING (independently), was, in fact, only as an amendment to "LIFE". Therefore, their research and systematization is carried out within the framework of microbiology exclusively "on the right" - according to the similarity and likeness of Living Cells, their structural studies, as shown above, are not actually systematized and do not give a MEASURE OF VIRALITY, but only its indication.
In this case, the General Dimensional Effect falls out of consideration, with the necessity following from NANO-Physics and Chemistry [12].
It falls out as "on the left" - at the stage of formation of the simplest viruses (there are a huge number of them and it is easy to assume that at least one will be found in order to start the "Chain Reaction" of their reproduction under certain conditions).
So it falls out and "on the right." Which virus kills a Living Cell is considered, but from the Dead Nature - Living Nature scale, it fell out completely as a "Dead" virus arose. The Living Cell is not considered at all.
So the General Physico-Chemical Dimensional Effect [13] falls out, which is the DEFINING one, and only secondary, indirect effects are analyzed.
And this is a misfortune not only for virology, but also for all modern Science, which has degenerated into the industry of a compiling set of knowledge due to the neglect of Fundamental Ideas, which even concerns the exact sciences.
Therefore, it is so important to understand the level of LIFE origin, the study of purely physical and chemical aspects of the Dimensional Effect "on the left", which can be analytically continued to a certain depth "on the right".
So, in the most General terms, there are a number of the most General Questions relating specifically to virology.
1. Systematization of particles intermediate between fullerenes and viruses - systematization of protoviruses. The approach used to describe "living" incommensurate crystals[14]can be applied.
2. Systematization of vibrations, intermediate between the "dead" Harmonic Oscillations and the NOTES of the Music of Life - the proto-NOTE of Life.
3. Purely physicochemical studies of bulk and surface properties. Virus-like particles REFERENCES RÉFERENCES RÉFERENCIAS 1. Stanislav V. Ordin, "Science and Society during COVID-19 Pandemic", Letter to Editor in the upcoming issue of IAAM's official diamond open access journal "Advanced Materials Proceedings",(ISSN: 2002-4428, e ISSN: 2000-441X), 2021, Volume 6, Issue 1, Pages 1-2, DOI: 10.5185/amp.2021.010417, https://www.iaamonline.org/advanced-materials-proceedings 2. The Universal Virus Database ICTVdB. Дата образецberry: 13 лесабра 2007. Апхинвровию из оригиная 13 лесабра 2007 рда.
3. How many viruses on Earth? Дага образець: 14 Марта 2017. Ахнвровано 21 Марта 2020 за.
4. Lawrence C. M., Menon S., Eilers B. J., et al. Structural and functional studies of archaeal viruses
5. Lawrence C. M., Menon S., Eilers B. J., et al. Structural and functional studies of archaeal viruses (aHrI.) // J. Biol. Chem.: journal. — 2009. — Vol. 284, no. 19. — P. 12599—12603. — doi:10.1074/jbc.R800078200. — PMID 19158076. — PMC 2675988. ApxHBnpoBaHo 24 HIOJIa 2018 roJa.
6. Gardner, Martin (October 1970). "The fantastic combinations of John Conway's new solitaire game 'life' (PDF). Mathematical Games. Scientific American. 223 (4): 120-123. DOI: 10.1038/scientificamerican1070-120. JSTOR 24927642.
7. Stanislav Ordin, "Characterization of the polymeric state of matter." Advanced Journal of Physics Research and Applications.AJPRA-RW-22-06,
[email protected],
8. Stanislav Ordin, «Bio-Characterization of the polymeric state of matter», Open Access Journal of Biomedical Science (OAJBS), Article ID: OAJBS-BM-22-RW-277
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10. Lectures of the St. Petersburg Meeting of Nobel Prize Laureates "Science and Human Progress", June 16-21, 2003
A. Gyver: "Electric Biosensor",
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C. de Dune "Singularities in the origin and evolution of life"
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14. S.V. Ordin, in Book: Optical Lattices: Structures, Atoms and Solitons, "Giant spatial dispersion in the region of plasmon-phonon interaction in one-dimensional- incommensurate crystal the higher silicide of manganese (HSM)", Editors: Benjamin J. Fuentes, Nova Sc. Publ. Inc., 2011, pp. 101-130. 241, ISBN: 978-1-61324-937-6
