Uterine Fibroids. What We Know and What We Need to Know

Uterine Fibroids. What We Know and What We Need to Know

Maria Korchagina

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Uterine Fibroids. What We Know and What We Need to Know

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Abstract

Uterine fibroids (UFs) are the most common tumours of the female reproductive system and represent a significant health issue worldwide. UFs develop during reproductive span and often shrink after menopause.UFs affect over 70% of women by the onset of menopause. Uterine fibroids arise from myometrial smooth muscle cells. UFs can be solitary or multiply and their size varies from microscopic to giant. Nowadays the exact cause of UFs remains unknown, but it is assumed that genetic abberations along with steroid hormones and growth factors play a pivotal role in thetumour development. In most cases UFs are asymptomaticand therefore it is difficult to estimate their actual prevalence. Symptomatic UFs present with abnormal menstrual bleeding, pelvic and low back pain, bulk symptoms, infertility and have a strong impact on health-related-quality-of-life (HRQL). Early diagnosisand treatment of UFs as well as preventive measures, especially for patients from high-risk groups, should be a priority. This article presents current data about pathophysiology, diagnosisandmanagement of UFs.

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How to Cite This Article

Maria Korchagina. 2026. \u201cUterine Fibroids. What We Know and What We Need to Know\u201d. Global Journal of Medical Research - E: Gynecology & Obstetrics GJMR-E Volume 22 (GJMR Volume 22 Issue E2).

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-E Classification DDC Code: 618.175 LCC Code: RG186

Submission ReceivedFebruary 17, 2022
Peer Review Double Blind
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Accepted February 25, 2022
Published July 9, 2022

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