From the Histological Model to the Mutational Model: The Study of Heavy Metals and Other Substances in New Antineoplastic Therapies

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PDDTM1FGV4

Ensuring safety and efficacy in new antiosteoplastic treatments involving heavy metals.

From the Histological Model to the Mutational Model: The Study of Heavy Metals and Other Substances in New Antineoplastic Therapies

Pasquale Ruffolo
Pasquale Ruffolo
Osvaldo Acquaviva
Osvaldo Acquaviva
Pierpaolo Capece
Pierpaolo Capece
Bruno Ruffolo
Bruno Ruffolo
Manuela Panunzio
Manuela Panunzio
Alessandra Paraggio
Alessandra Paraggio
Andrea Ruffolo
Andrea Ruffolo
DOI

Abstract

The study of genetic mutations in tumours changes the therapeutic approach; in fact, we move into a different advanced and strategic phase by entering personalized precision medicine and shifting the focus from the tissue study of the tumour to the modification and proliferation of neoplastic cells. The therapeutic programs, especially in oncology, are changing. We are in a phase of transition from the histological model to the model of genetic mutation (mutation). When a person’s immune defences do not respond to a disease it is because the body cannot produce or activate specific lymphocytes and antibodies against that disease. This causes of a lack of therapeutic response or recurrence of the disease.

From the Histological Model to the Mutational Model: The Study of Heavy Metals and Other Substances in New Antineoplastic Therapies

The study of genetic mutations in tumours changes the therapeutic approach; in fact, we move into a different advanced and strategic phase by entering personalized precision medicine and shifting the focus from the tissue study of the tumour to the modification and proliferation of neoplastic cells. The therapeutic programs, especially in oncology, are changing. We are in a phase of transition from the histological model to the model of genetic mutation (mutation). When a person’s immune defences do not respond to a disease it is because the body cannot produce or activate specific lymphocytes and antibodies against that disease. This causes of a lack of therapeutic response or recurrence of the disease.

Pasquale Ruffolo
Pasquale Ruffolo
Osvaldo Acquaviva
Osvaldo Acquaviva
Pierpaolo Capece
Pierpaolo Capece
Bruno Ruffolo
Bruno Ruffolo
Manuela Panunzio
Manuela Panunzio
Alessandra Paraggio
Alessandra Paraggio
Andrea Ruffolo
Andrea Ruffolo

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Pasquale Ruffolo. 2026. “. Global Journal of Medical Research – B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 23 (GJMR Volume 23 Issue B1): .

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-B Classification: NLM Code: QZ 200
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From the Histological Model to the Mutational Model: The Study of Heavy Metals and Other Substances in New Antineoplastic Therapies

Pasquale Ruffolo
Pasquale Ruffolo
Osvaldo Acquaviva
Osvaldo Acquaviva
Pierpaolo Capece
Pierpaolo Capece
Bruno Ruffolo
Bruno Ruffolo
Manuela Panunzio
Manuela Panunzio
Alessandra Paraggio
Alessandra Paraggio
Andrea Ruffolo
Andrea Ruffolo

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