A Prospective Cohort Study of Death Related to Opioid Use in Older Patients with a Diagnosis of Cancer
Context: Opioids use in older adults with cancer is growing, as do world population over 60 years of age. Objectives: This study aimed to evaluate the association between the use of opioids and death in older patients with a cancer diagnosis. Methods: We performed the analysis in a prospective cohort study with an internal comparison group. Statistical modeling considered clinical and laboratory variables. The cohort included 747 patients. Of these, 59 patients were using opioids, and they were selected to form the exposed group. Of the remaining 688, 59 were randomized to compose the group not exposed to opioids.
