Comparative Efficacy, Safety and Cost Analysis of Amisulpride vs Olanzapine for Treatment of Schizophrenia
Schizophrenia is a psychiatric disorder associated with a range of psychological, behavioural and cognitive problems especially. Nowadays, atypical antipsychotics are the mainstay for the treatment of shizophrenia. Among them amisulpride and olanzapine are the most commonly used atypical antipsychotics. The objective of this study is to compare the efficacy, safety and cost analysis of amisulpride vs olanzapine for the treatment of schizophrenia. It is a double blind, randomised control clinical trial conducted over a period of 12 weeks. A total of 90 patients were included which were randomly divided into two groups. Group A consisting of 39 patients who received amisulpride tablet( 400mg/day) and group B consisting of 38 patients received olanzapine tablet (10mg/day). The brief psychiatric rating scale (BPRS) was taken as main evaluation parameter for the effectiveness of treatment.
