Development and Validation of a Stability-Indicating RP-HPLC Method for the Simultaneous Determination of Sofosbuvir, Velpatasvir, and Voxilaprevir in Tablet Formulation

Development and Validation of a Stability-Indicating RP-HPLC Method for the Simultaneous Determination of Sofosbuvir, Velpatasvir, and Voxilaprevir in Tablet Formulation

Deepthi R

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Gowri Sankar D

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Development and Validation of a Stability-Indicating RP-HPLC Method for the Simultaneous Determination of Sofosbuvir, Velpatasvir, and Voxilaprevir in Tablet Formulation

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Sandhya Rani,J Devanna,N (2018). Development and validation of RP-HPLC method for the simultaneous estimation of Sofosbuvir, velpatasvir, and voxilaprevir in bulk and tablet dosage forms.
Sandhya Rani,J Devanna,N (2017). New RP-HPLC method development and validation for simultaneous estimation of sofosbuvir and velpatasvir in a pharmaceutical dosage form.
Geetha Susmitha,A Rajitha,G (2018). Development and validation of stability indicating UPLC method for simultaneous estimation of sofosbuvir and velpatasvir in a tablet dosage form.
Lakshmana Rao,A Pallavi,A (2019). Method Development and Validation of Stability Indicating RP-HPLC Method for Simultaneous Estimation of Sofosbuvir and Velpatasvir in Tablet Dosage Form.
B; Balaswami,P Ramana,; Venkata,B Rao,P Subba; Sanjeeva (2018). A New Simple Stability-Indicating RP-HPLC-PDA Method for Simultaneous Estimation of Triplicate Mixture of Sofosbuvir, Velpatasvir, and Voxilaprevir in Tablet Dosage Form.
Memthoibi Devi,L,Dr Rama Mohan Reddy,T Dr,K Abbulu (2010). Simultaneous determination and validation of third generation antiviral drugs by RP-HPLC method.
K Lalitha,Raveendra Reddy,J Devanna,N (2018). Stability indicating RP-HPLC method development and validation for estimation of Sofosbuvir in a pharmaceutical dosage form.
Phillip Borman,David Elder (2005). Q2(R1) Validation of Analytical Procedures.
(1996). ICH: Q2B. Harmonized Tripartite Guideline, Validation of Analytical Procedure: Methodology, IFPMA.
G Ngwa (2010). Forced degradation studies as an integral part of HPLC stability indicating method development.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Deepthi R. 2020. \u201cDevelopment and Validation of a Stability-Indicating RP-HPLC Method for the Simultaneous Determination of Sofosbuvir, Velpatasvir, and Voxilaprevir in Tablet Formulation\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 20 (GJMR Volume 20 Issue B3).

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GJMR Volume 20 Issue B3

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-B Classification NLMC Code: QV 55

Submission ReceivedDecember 6, 2019
Peer Review Double Blind
Handling Editor
Accepted January 3, 2020
Published January 15, 2020

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v1.2

Issue date

April 7, 2020

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