Phenolic Profile, Anti-Inflammatory and Diuretic Properties of Asplenium Ceterach Tested on Albino Mice and Wistar Albino Rats

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PDDTM0GB4R

Phenolic Profile, Anti-Inflammatory and Diuretic Properties of Asplenium Ceterach Tested on Albino Mice and Wistar Albino Rats

Mostapha Bachir bey
Mostapha Bachir bey University of Bejaia
Rekia Sidhoum
Rekia Sidhoum
Latifa Halli
Latifa Halli
Othmane Yalaoui
Othmane Yalaoui
Asma Belkadi
Asma Belkadi
DOI

Abstract

Asplenium ceterach is a fern used in traditional medicine against kidney stones and as a diuretic agent. Thus, we set as objective of this study is the determination of the phenolic profile as well as the study of anti-inflammatory and diuretic properties of Asplenium ceterach (Rustyback). Phenolic composition is achieved by High-performance liquid chromatography, the anti-inflammatory activity is determined in albino mice, and the diuretic activity in Wistar albino rats. The results of phenolic profile show an overall concentration of 3926 μg/g DM of Asplenium ceterach, of which 3/4 are represented by chlorogenic acid. This plant is endowed with an interesting plantar anti-inflammatory property and a topical anti-inflammatory comparable to that of ibuprofen. Asplenium ceterach expresses an excellent diuretic activity significantly higher that of Furosemide. This study confirms the traditional use of the infusion of Asplenium ceterach as a powerful diuretic and an anti-inflammatory.

Phenolic Profile, Anti-Inflammatory and Diuretic Properties of Asplenium Ceterach Tested on Albino Mice and Wistar Albino Rats

Asplenium ceterach is a fern used in traditional medicine against kidney stones and as a diuretic agent. Thus, we set as objective of this study is the determination of the phenolic profile as well as the study of anti-inflammatory and diuretic properties of Asplenium ceterach (Rustyback). Phenolic composition is achieved by High-performance liquid chromatography, the anti-inflammatory activity is determined in albino mice, and the diuretic activity in Wistar albino rats. The results of phenolic profile show an overall concentration of 3926 μg/g DM of Asplenium ceterach, of which 3/4 are represented by chlorogenic acid. This plant is endowed with an interesting plantar anti-inflammatory property and a topical anti-inflammatory comparable to that of ibuprofen. Asplenium ceterach expresses an excellent diuretic activity significantly higher that of Furosemide. This study confirms the traditional use of the infusion of Asplenium ceterach as a powerful diuretic and an anti-inflammatory.

Mostapha Bachir bey
Mostapha Bachir bey University of Bejaia
Rekia Sidhoum
Rekia Sidhoum
Latifa Halli
Latifa Halli
Othmane Yalaoui
Othmane Yalaoui
Asma Belkadi
Asma Belkadi

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Mostapha Bachir bey. 2020. “. Global Journal of Medical Research – B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 20 (GJMR Volume 20 Issue B6): .

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-B Classification: NLMC Code: QV 744
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Phenolic Profile, Anti-Inflammatory and Diuretic Properties of Asplenium Ceterach Tested on Albino Mice and Wistar Albino Rats

Mostapha Bachir bey
Mostapha Bachir bey University of Bejaia
Rekia Sidhoum
Rekia Sidhoum
Latifa Halli
Latifa Halli
Othmane Yalaoui
Othmane Yalaoui
Asma Belkadi
Asma Belkadi

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