Tranexamic Acid Coated or Eluted Uterine Balloon and Co- Attached Cervical Shutter in Post Partum Haemorrhage. A New Combatant in the Armamentarium, Not Merely a Balloon but More

Tranexamic Acid Coated or Eluted Uterine Balloon and Co- Attached Cervical Shutter in Post Partum Haemorrhage. A New Combatant in the Armamentarium, Not Merely a Balloon but More

Abd El Aal Nasser Kamal

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Tranexamic Acid Coated or Eluted Uterine Balloon and Co- Attached Cervical Shutter in Post Partum Haemorrhage. A New Combatant in the Armamentarium, Not Merely a Balloon but More

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Abstract

Described herein a Tranexamic Acid (TXA) -Coated or Eluted Uterine Balloon for use in an intra uterine location for primary management of postpartum haemorrhage (PPH). It enforces the tamponade effect of currently used non medicated uterine balloons with an additional inbuilt mechanism of local steady release of the antibrinolytic TXA into uterine cavity that has been evidenced to contribute to haemostasis in cases of PPH. The invention ushers a new era of utilizing the uterine balloon surface coat as a delivery vehicle for TXA. This can be achieved via different techniques including and not limited to matrix coating or eluting of nanoparticulate TXA in the outermost layer of the balloon .TXA coated or eluted balloon replenish non medicated balloons with a therapeutic modality of the TXA relatedantifibrinolysis especially in hemorrhages known to be associated with coagulopathy.

References

13 Cites in Article

Reference Format

(2006). ACOG Practice Bulletin: Clinical Management Guidelines for Obstetrician-Gynecologists Number 76, October 2006: postpartum hemorrhage.
K Khan,D Wojdyla,L Say,Gülmezoglu Van Look,P (2006). WHO analysis of causes of maternal death: a systematic review.
A Lalonde,B Daviss,A Acosta,K Herschderfer (1994). Postpartum hemorrhage today: ICM/FIGO initiative 2004–2006.
Y Bakri,A Amri,F Abdul Jabbar (1974). Tamponade‐balloon for obstetrical bleeding.
G Dildy,S Clark (1993). Pelvic pressure pack for catastrophic postpartum hemorrhage.
G Condous,S Arulkumaran,I Symonds,R Chapman,A Sinha,K Razvi (2003). The “Tamponade Test” in the Management of Massive Postpartum Hemorrhage.
W Chantrapitak,K Srijuntuek,R Wattanaluangarun (2011). The efficacy of lower uterine segment compression for prevention of early postpartum hemorrhage after vaginal delivery.
Panagiotis Peitsidis,Rezan Kadir (2011). Antifibrinolytic therapy with tranexamic acid in pregnancy and postpartum.
K Ker,P Edwards,P Perel,H Shakur,I Roberts (2012). Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
H Shakur,I Roberts,R Bautista (2010). Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
Andrea Dell’amore,Guido Caroli,Asadi Nizar,Nicola Cassanelli,Giulia Luciano,Domenico Greco,Giampiero Dolci,Alessandro Bini,Franco Stella (2012). Can Topical Application of Tranexamic Acid Reduce Blood Loss in Thoracic Surgery? A Prospective Randomised Double Blind Investigation.
Hosam Fawzy,Elsayed Elmistekawy,Daniel Bonneau,David Latter,Lee Errett (2009). Can local application of Tranexamic acid reduce post-coronary bypass surgery blood loss? A randomized controlled trial.
Jean Wong,Hossam El Beheiry (2011). Topical Tranexamic Acid to Reduce Postoperative Blood Loss in Total Knee Arthroplasty.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Abd El Aal Nasser Kamal. 2018. \u201cTranexamic Acid Coated or Eluted Uterine Balloon and Co- Attached Cervical Shutter in Post Partum Haemorrhage. A New Combatant in the Armamentarium, Not Merely a Balloon but More\u201d. Global Journal of Medical Research - E: Gynecology & Obstetrics GJMR-E Volume 18 (GJMR Volume 18 Issue E4): .

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GJMR Volume 18 Issue E4
Pg. 13- 22

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

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Classification

GJMR-E Classification: NLMC Code: WP 440

Submission ReceivedDecember 8, 2017
Peer Review Double Blind
Handling Editor
Accepted January 2, 2018
Published January 15, 2018

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v1.2

Issue date

December 19, 2018

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Article Matrices

Total Score: 101

Country: Egypt

Subject: Global Journal of Medical Research - E: Gynecology & Obstetrics

Authors: Abd El Aal Nasser Kamal (PhD/Dr. count: 0)

View Count (all-time): 119

Total Views (Real + Logic): 2774

Total Downloads (simulated): 1444

Publish Date: 2018 12, Wed

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Total Views: 2774

Total Downloads: 1444

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