Detection of Intron22 Mutations in Iraqi Female Carriers in Wasit Province with Hemophilia A

Maysoon Mohammed Hassan
Maysoon Mohammed Hassan
University of Wasit University of Wasit

Send Message

To: Author

Detection of Intron22 Mutations in Iraqi Female Carriers in Wasit Province with Hemophilia A

Article Fingerprint

ReserarchID

8X90O

Detection of Intron22 Mutations in Iraqi Female Carriers in Wasit Province with Hemophilia A Banner

AI TAKEAWAY

Connecting with the Eternal Ground
  • English
  • Afrikaans
  • Albanian
  • Amharic
  • Arabic
  • Armenian
  • Azerbaijani
  • Basque
  • Belarusian
  • Bengali
  • Bosnian
  • Bulgarian
  • Catalan
  • Cebuano
  • Chichewa
  • Chinese (Simplified)
  • Chinese (Traditional)
  • Corsican
  • Croatian
  • Czech
  • Danish
  • Dutch
  • Esperanto
  • Estonian
  • Filipino
  • Finnish
  • French
  • Frisian
  • Galician
  • Georgian
  • German
  • Greek
  • Gujarati
  • Haitian Creole
  • Hausa
  • Hawaiian
  • Hebrew
  • Hindi
  • Hmong
  • Hungarian
  • Icelandic
  • Igbo
  • Indonesian
  • Irish
  • Italian
  • Japanese
  • Javanese
  • Kannada
  • Kazakh
  • Khmer
  • Korean
  • Kurdish (Kurmanji)
  • Kyrgyz
  • Lao
  • Latin
  • Latvian
  • Lithuanian
  • Luxembourgish
  • Macedonian
  • Malagasy
  • Malay
  • Malayalam
  • Maltese
  • Maori
  • Marathi
  • Mongolian
  • Myanmar (Burmese)
  • Nepali
  • Norwegian
  • Pashto
  • Persian
  • Polish
  • Portuguese
  • Punjabi
  • Romanian
  • Russian
  • Samoan
  • Scots Gaelic
  • Serbian
  • Sesotho
  • Shona
  • Sindhi
  • Sinhala
  • Slovak
  • Slovenian
  • Somali
  • Spanish
  • Sundanese
  • Swahili
  • Swedish
  • Tajik
  • Tamil
  • Telugu
  • Thai
  • Turkish
  • Ukrainian
  • Urdu
  • Uzbek
  • Vietnamese
  • Welsh
  • Xhosa
  • Yiddish
  • Yoruba
  • Zulu
Font Type
Font Size
Font Size
Bedground

References

40 Cites in Article
  1. A James (2005). More than menorrhagia: a review of the obstetric and gynaecological manifestations of bleeding disorders.
  2. L Salazar-Sánchez,G Jiménez-Cruz,M Mendez,P Chaverri,P Alvarado,W Schröder,K Wulff,M Sandoval,F Herrmann,A Pavlova,J Oldenburg (2010). Molecular analysis of FVIII gene in severe HA patients of Costa Rica.
  3. P Fogarty,C Kessler,B Hemophilia (2013). Consultative Hemostasis and Thrombosis.
  4. N Bogdanova,A Markoff,R Eisert,C Wermes,H Pollmann,A Todorova,M Chlystun,Nowak-Göttlu,J Horst (2007). Spectrum of molecular defects and mutation detection rate in patients with mild and moderate hemophilia A.
  5. A Anjali,Manuel Sharathkumar,Carcao (2011). Clinical Advances in Hemophilia Management.
  6. P Fay (1988). Reconstitution of human factor VIII from isolated subunits.
  7. P Botton,K Maggs,A Hemophilia,B (2003). Unknown Title.
  8. J Graw,H Brackmann,J Oldenburg,R Schneppenheim,M Spannagl,R Schwaab (2005). Hemophilia A: From mutation analysis to new therapies.
  9. C Kasper,C Buzin (2009). Genetics of Hemophilia A and B. An Introduction for Clinicians.
  10. V Byams,P Kouides,R Kulkarni,J Baker,D Brown,J Gill,A Grant,A James,B Konkle,J Maahs,M Dumas,S Mcalister,D Nance,D Nugent,C Philipp,J Soucie,E Stange (2011). Surveillance of female patients with inherited bleeding disorders in United States Haemophilia Treatment Centres.
  11. J Haldane (1935). The rate of spontaneous mutation of a human gene.
  12. Ulla Hedner,David Ginsburg,Jeanne Lusher,Katherine High (2000). Congenital Hemorrhagic Disorders: New Insights into the Pathophysiology and Treatment of Hemophilia.
  13. Jane Gitschier,William Wood,Therese Goralka,Karen Wion,Ellson Chen,Dennis Eaton,Gordon Vehar,Daniel Capon,Richard Lawn (1984). Characterization of the human factor VIII gene.
  14. R Bagnall,N Waseem,P Green,F Giannelli (2002). recurrent inversion breaking intron 1 of the factor VIII gene is a frequent cause of severe hemophilia A.
  15. Delia Lakich,Haig Kazazian,Stylianos Antonarakis,Jane Gitschier (1993). Inversions disrupting the factor VIII gene are a common cause of severe haemophilia A.
  16. Judith Rosslter,Michele Young,Michelle Kimberland,Pierre Hutter,Rhett Ketterling,Jane Gitschier,Jürgen Horst,Michael Morris,Daniel Schaid,Phillppe De Moerloose,Steve Sommer,Haig Kazazian,Styllanos Antonarakis (1994). Factor VIII gene inversions causing severe hemophilia A originate almost exclusively in male germ cells.
  17. R Bagnall,F Giannelli,P Green (2005). Polymorphism and hemophilia A causing inversions in distal Xq28: a complex picture.
  18. R Bagnall,F Giannelli,P Green (2006). Int22h-related inversions causing hemophilia A: a novel insight into their origin and a new more discriminant PCR test for their detection.
  19. S Antonarakis,J Rossiter,M Young,J Horst,P De Moerloose,S Sommer,R Ketterling,Hh Kazazian,C Negrier,C Vinciguerra (1995). Factor VIII gene inversions in severe hemophilia A: results of an international consortium study.
  20. C De Brasi,D Bowen (2008). Molecular characteristics of the intron 22 homologs of the coagulation factor VIII gene: an update.
  21. Liliana Miguel Martín Abelleyro,Carmen Rossetti,Claudia Radic,Miguel Candela,Irene Larripa,Carlos Daniel,De Brasi (2012). Are int22h-mediated deletions a common cause of hemophilia?.
  22. H Youssoufian,H Kazazian,D Phillips,S Aronis,G Tsiftis,V Brown,S Antonarakis (1986). Recurrent mutations in hemophilia A give evidence for CpG mutation hotspots.
  23. B Levinson,S Kenwrick,D Lakich,G Hammonds,J Gitschier (1990). A transcribed gene in an intron of the human factor VIII gene.
  24. Barbara Levinson,Susan Kenwrick,Pamela Gamel,Karen Fisher,Jane Gitschier (1992). Evidence for a third transcript from the human factor VIII gene.
  25. D Freije,D Schlessinger (1992). 1.6-Mb contig of yeast artificial chromosomes around the human factor VIII gene reveals three regions homologous to probes for the DXS115 locus and two for the DXYS64 locus.
  26. M Peters,C Ross (2001). Isolation of a 40 k-Da Huntingtin -associated protein.
  27. K Frazer,S Murray,N Schork,E Topol (2009). Human genetic variation and its contribution to complex traits.
  28. Jennifer Naylor,Astrid Brinke,Shella Hassock,Peter Green,Francesco Giannelli (1993). Characteristic mRNA abnormality found in half the patients with severe haemophilia A is due to large DNA inversions.
  29. S Preethi,D Shrimati,S Chandrakala,G Kanjaksha (2014). Mutations in Intron 1 and Intron 22 Inversion Negative Haemophilia A Patients from Western India.
  30. Mantilla Capacho,J Beltrán-Miranda,C Luna-Záizar,H Aguilar-López,L Esparza-Flores,M López-Guido,B Troyo-Sanromán,R Jaloma-Cruz,A (2007). Frequency of intron 1 and 22 inversions of Factor VIII gene in Mexican patients with severe hemophilia A.
  31. J Becker,R Schwaab,A Möller-Taube,U Schwaab,W Schmidt,H Brackmann,T Grimm,K Olek,J Oldenburg (1996). Characterization of the factor VIII defect in 147 patients with sporadic hemophilia A: family studies indicate a mutation type-dependent sex ratio of mutation frequencies.
  32. J Naylor,P Green,F Giannelli,C Rizza (1992). Factor VIII gene explains all cases of haemophilia A.
  33. M Martín-Salces,A Venceslá,M Alvárez-Román,I Rivas,I Fernandez,N Butta,M Baena,P Fuentes-Prior,E Tizzano,V Jiménez-Yuste (2010). Clinical and genetic findings in five female patients with haemophilia A: Identification of a novel missense mutation, p. Phe2127.
  34. Pier Mannucci,Edward Tuddenham (2001). The Hemophilias — From Royal Genes to Gene Therapy.
  35. C Ludlam,K Pasi,P Bolton-Maggs,P Collins,A Cumming,G Dolan,A Fryer,C Harrington,F Hill,I Peake,D Perry,H Skirton,M Smith (2005). A framework for genetic service provision for haemophilia and other inherited bleeding disorders.
  36. S Thomas,D Herbert,A Street,C Barnes,J Boal,P Komesaroff (2007). Attitudes towards and beliefs about genetic testing in the haemophilia community: a qualitative study.
  37. C Chi,N Shiltagh,C Kingman,D Economides,C Lee,R Kadir (2006). Identification and management of women with inherited bleeding disorders: a survey of obstetricians and gynaecologists in the United Kingdom.
  38. I Plug,E Mauser-Bunschoten,A Brocker-Vriends,H Van Amstel,J Van Der Bom,J Van Diemen-Homan,J Willemse,F Rosendaal (2006). Bleeding in carriers of hemophilia.
  39. A Laurie,A Hill,J Harraway,A Fellowes,G Phillipson,P Benny,M Smith,P George (2010). Preimplantation genetic diagnosis for hemophilia A using indirect linkage analysis and direct genotyping approaches.
  40. I Peake,D Lillicrap,V Boulyjenkov,E Bri??t,V Chan,E Ginter,E Kraus,R Ljung,P Mannucci,K Nicolaides,E Tuddenham (1993). Report of a joint WHO/WFH meeting on the control of haemophilia.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Maysoon Mohammed Hassan. 2017. \u201cDetection of Intron22 Mutations in Iraqi Female Carriers in Wasit Province with Hemophilia A\u201d. Global Journal of Medical Research - F: Diseases GJMR-F Volume 17 (GJMR Volume 17 Issue F1).

Download Citation

Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords
Classification
GJMR-F Classification NLMC Code: WH 325
Version of record

v1.2

Issue date
March 1, 2017

Language
en
Experiance in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

Article Matrices
Total Views: 3726
Total Downloads: 1889
2026 Trends
Related Research
Our website is actively being updated, and changes may occur frequently. Please clear your browser cache if needed. For feedback or error reporting, please email [email protected]

Request Access

Please fill out the form below to request access to this research paper. Your request will be reviewed by the editorial or author team.
X

Quote and Order Details

Contact Person

Invoice Address

Notes or Comments

This is the heading

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.

High-quality academic research articles on global topics and journals.

Detection of Intron22 Mutations in Iraqi Female Carriers in Wasit Province with Hemophilia A

Maysoon Mohammed Hassan
Maysoon Mohammed Hassan <p>University of Wasit</p>

Research Journals