Formulation and Control of Biodegradable Injectable In Situ Gelling System of Levonorgestrel

Formulation and Control of Biodegradable Injectable In Situ Gelling System of Levonorgestrel

Article ID

27279

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Formulation and Control of Biodegradable Injectable In Situ Gelling System of Levonorgestrel

Dr. pegah dadras

rasoul Dinarvand

seyed

mostafa khezri

DOI

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Abstract

The aim of this study was to develop a new polymeric gel that used as a contraceptive system.Polymeric gel has been studied extensively for drug delivery systems. In this article, thermal- sensitive poly (DL-lactic acid)-poly (ethylene glycol) – poly (DL-lactic acid) (PLA-PEG-PLA) hydrogel was used as an implantable contraceptive system.Aqueous solution of this copolymer fromed a free flowing so at room temperature and became a gel at body temperature. In this study, the biodegradable copolymer with molecular structure of PLA-PEG-PLA was synthesized and was investigated the sol-gel transition, hydrolytic degradation and In-vitro drug delivery from the system. In the current studyLevonorgestrel was selected as a model contraceptive drug.

Formulation and Control of Biodegradable Injectable In Situ Gelling System of Levonorgestrel

Authors

Dr. pegah dadras

rasoul Dinarvand

seyed

mostafa khezri

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How to Cite

Seyed Mostafa Khezri. 2011. “. Global Journal of Research in Engineering – J: General Engineering GJRE-J Volume 11 (GJRE Volume 11 Issue J7): .

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Journal Specifications

Crossref Journal DOI 10.17406/gjre

Print ISSN 0975-5861

e-ISSN 2249-4596

GJRE Volume 11 Issue J7
Pg. 15- 20

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Submission Received May 16, 2011
Accepted June 11, 2011
Published June 22, 2011

Keywords

biodegradable in situ injectable sol-gel transition thermal-sensitive

Article Matrices

Total Score: 89

Country: Iran

Subject: Global Journal of Research in Engineering - J: General Engineering

Authors: Dr. pegah dadras,rasoul Dinarvand,seyed,mostafa khezri, (PhD/Dr. count: 1)

View Count (all-time): 171

Total Views (Real + Logic): 5473

Total Downloads (simulated): 2886

Publish Date: 2011 12, Sat

Monthly Totals (Real + Logic):

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Total Views: 5473

Total Downloads: 2886

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