Is there a relationship between intraoperative bispectral index and cognitive impairment after coronary artery surgery?

Dr. Judith A. Hudetz

Is there a relationship between intraoperative bispectral index and cognitive impairment after coronary artery surgery?

Dr. Judith A. Hudetz * §

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§ Clement J. Zablocki VA Medical Center

Is there a relationship between intraoperative bispectral index and cognitive impairment after coronary artery surgery?

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Abstract

We examined the relationship between short- and medium-term POCD and anesthetic depth using bispectral index (BIS) values in patients undergoing coronary artery bypass graft (CABG) surgery using cardiopulmonary bypass (CPB). We identified 89 patients in whom BIS monitoring was used. Memory and executive functions were assessed before, one week, and three months after surgery. Two cognitive tests showed at least two standard deviation (SD) decrease from baseline in patients one week after surgery. After three months, six tests showed at least one SD decrease from baseline. BIS scores were significantly higher after CPB in patients with versus without POCD one week after surgery. The BIS scores during and after CPB and throughout the surgery were also higher in patients with versus without POCD three months after surgery. The results suggest that there may be a relationship between POCD and anesthetic depth in patients undergoing CABG.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Dr. Hudetz. 1970. "Is there a relationship between intraoperative bispectral index and cognitive impairment after coronary artery surgery?". Global Journal of Medical Research, Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 11 (GJMR Volume 11 Issue B4).

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GJMR Volume 11 Issue B4

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Journal Specifications

Crossref Journal DOI 10.17406/gjmr

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

bispectral index monitoring cardiopulmonary bypass coronary artery surgery postoperative cognitive dysfunction

Classification

GJMR-B Classification NLMC Code: WG 420

WG 166WG

Submission ReceivedSeptember 15, 2011
Peer Review Double Blind
Handling Editor
Accepted October 10, 2011
Published October 20, 2011

Version of record

v1.2

Language

English

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Article Matrices

Total Score: 180

Country: United States

Subject: Global Journal of Medical Research

Authors: Dr. Judith A. Hudetz,Zafar Iqbal,Sweeta D. Gandhi,Kathleen M. Patterson,Paul S. Pagel, (PhD/Dr. count: 1)

View Count (all-time): 193

Total Views (Real + Logic): 7616

Total Downloads (simulated): 491

Publish Date: 2011 10, Thu

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Total Views: 7.6K

Total Downloads: 491

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