L-lysine Neuro-Dynamic Optimal Control

Article ID

5X74P

L-lysine Neuro-Dynamic Optimal Control

Dr. Tatiana Ilkova
Dr. Tatiana Ilkova Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences
Dr. Mitko Petrov
Dr. Mitko Petrov
DOI

Abstract

In this paper Neuro-dynamic programming (NDP) is proposed as an alternative to alleviate the “curse of dimensionality” of the Dynamic programming (DP) for optimal control of a fed-batch fermentation process in the L-lysine production. The most effective and cheapest method for the Llysine biosynthesis (in biological active form) is the microbiological method via a direct fermentation. In this paper an optimization method of the L-lysine production from strain Brevibacterium flavum 22LD is used and that is NDP. The results show that the quality of L-lysine enhances at the end of the process. The proposed method is particularly simple to implement and can be applied for on-line optimization.

L-lysine Neuro-Dynamic Optimal Control

In this paper Neuro-dynamic programming (NDP) is proposed as an alternative to alleviate the “curse of dimensionality” of the Dynamic programming (DP) for optimal control of a fed-batch fermentation process in the L-lysine production. The most effective and cheapest method for the Llysine biosynthesis (in biological active form) is the microbiological method via a direct fermentation. In this paper an optimization method of the L-lysine production from strain Brevibacterium flavum 22LD is used and that is NDP. The results show that the quality of L-lysine enhances at the end of the process. The proposed method is particularly simple to implement and can be applied for on-line optimization.

Dr. Tatiana Ilkova
Dr. Tatiana Ilkova Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences
Dr. Mitko Petrov
Dr. Mitko Petrov

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Dr. Tatiana Ilkova. 1970. “. Unknown Journal GJMR Volume 11 (GJMR Volume 11 Issue 4): .

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L-lysine Neuro-Dynamic Optimal Control

Dr. Tatiana Ilkova
Dr. Tatiana Ilkova Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences
Dr. Mitko Petrov
Dr. Mitko Petrov

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