A Study of Cost Effectiveness of Artemisinine Combination Therapy (Act) Among Paediatric Patients at a Tertiary Medical Centre in South West Nigeria

Dr. OMOLE Moses Kayode

A Study of Cost Effectiveness of Artemisinine Combination Therapy (Act) Among Paediatric Patients at a Tertiary Medical Centre in South West Nigeria

Dr. OMOLE Moses Kayode * §

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University of Ibadan.

A Study of Cost Effectiveness of Artemisinine Combination Therapy (Act) Among Paediatric Patients at a Tertiary Medical Centre in South West Nigeria

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Abstract

This retrospective study was to compare the cost effectiveness of oral ACT as a first line of treatment of malaria with non-oral ACTs in paediatric patients aged 5 years and below. The study was carried out at Children Outpatients Clinic of Federal Medical Centre, Abeokuta Ogun State in Nigeria between April and September 2005. Clinical case notes of paediatric patients aged 5 years and below were used. Three hundred and fifty (350) patients were randomly selected with only 328 patients meeting the inclusion criteria. The number consisted of 153 (46.6%) males and 175 (53.4%) females. The mean age of patients was 2.3 years (SD 1.4). Oral Chloroquine/Sulphadoxine and Pyrimethamine (CQ/SP) was administered to 127 (38.7%) patients, 113 (34.5%) patients had Quinine/Sulphadoxine and Pyrimethamine (QSP) while 88 (26.8% ) patients had Arthemisine/ Sulphadoxine, Pyrimethamine (ASP). The cure rate for CQ/SP, Quinine/SP and Arthemisine/SP were (11.0%), (22.1%) and (97.7%) respectively. It was only Artemisinine/SP that met the 7.5% efficacy rate recommended by WHO. Data on the therapeutic efficacy of the treatment given to the patients were collected and analyzed using descriptive statistics of frequency distribution and percentages with statistical package Microsoft SPSS 10.0 window version

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Dr. Kayode. 1970. "A Study of Cost Effectiveness of Artemisinine Combination Therapy (Act) Among Paediatric Patients at a Tertiary Medical Centre in South West Nigeria". Global Journal of Medical Research, Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 12 (GJMR Volume 12 Issue B6).

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GJMR Volume 12 Issue B6

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Journal Specifications

Crossref Journal DOI 10.17406/gjmr

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

ACTs Chloroquine Non ACTs Pyrimethamine Quinine Sulphadoxine

Classification

GJMR-B Classification WS 290

Submission ReceivedApril 26, 2012
Peer Review Double Blind
Handling Editor
Accepted May 21, 2012
Published June 2, 2012

Version of record

v1.2

Language

English

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Article Matrices

Total Score: 146

Country: Nigeria

Subject: Global Journal of Medical Research

Authors: Dr. OMOLE Moses Kayode & LAWAL Tajudeen A. (PhD/Dr. count: 1)

View Count (all-time): 213

Total Views (Real + Logic): 4888

Total Downloads (simulated): 323

Publish Date: 2012 06, Sat

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Total Views: 4.9K

Total Downloads: 323

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