Evaluation of total phenolic contents and antiulcerogenic activity of root bark of Azadirachta indica

Abstract

The effect of methanol extract of root bark of Azadirachta indica was investigated in mice to evaluate the antiulcerogenic activity. Total phenolics were also determined. The root Extracts were subjected to phytochemical analysis and total phenolics were also determined by the modified Folin-Ciocalteu method. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, pH, free acidity, total acidity, and ulcer index and % ulcer protection. The results indicated that the methanol extract significantly (p< 0.001) decreases volume of gastric acid secretion, pH, free acidity, total acidity and ulcer index and shows significant ulcer protection compared to standard control. Root bark extracts found to possess significant amount of phenolics and other biologically active constituents based on phytochemical evaluation and shows significant antiulcerogenic activity.

A Study of Conflict Issues Affecting Ugandan Housemaids who Migrate to Saudi Arabia and How to Mitigate them

March 10, 2026

This study aims to comprehensively analyse the complex interplay between