Synthesis and Antimicrobial Activity of Some New Nitrogen Heterocyclic Systems Bearing 1, 2, 4-Tiazine Moiety

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M5IT5

Synthesis and Antimicrobial Activity of Some New Nitrogen Heterocyclic Systems Bearing 1, 2, 4-Tiazine Moiety

Dr. Wafaa R. Abdel-Monem
Dr. Wafaa R. Abdel-Monem Department of Chemistry Faculty of Education Ain-Shams University, Roxy, 11757, Cairo, Egypt.
DOI

Abstract

Synthesis and antimicrobial activity of some new heterocycles such as pyrimidines, 1,2,4-triazoles, 1,2,4-triazines, 1,3-thiazoles and related compounds (2-26) bearing 1,2,4-triazine moiety have been prepared from the reaction of the 3-amino-5,6-diphenyl-1,2,4-triazine (1) with different organic reagents under different reaction conditions. Structures of the new synthesized compounds were confirmed by elemental analyses and spectral data. Some of the synthesized products were tested and evaluated as antimicrobial agents.

Synthesis and Antimicrobial Activity of Some New Nitrogen Heterocyclic Systems Bearing 1, 2, 4-Tiazine Moiety

Synthesis and antimicrobial activity of some new heterocycles such as pyrimidines, 1,2,4-triazoles, 1,2,4-triazines, 1,3-thiazoles and related compounds (2-26) bearing 1,2,4-triazine moiety have been prepared from the reaction of the 3-amino-5,6-diphenyl-1,2,4-triazine (1) with different organic reagents under different reaction conditions. Structures of the new synthesized compounds were confirmed by elemental analyses and spectral data. Some of the synthesized products were tested and evaluated as antimicrobial agents.

Dr. Wafaa R. Abdel-Monem
Dr. Wafaa R. Abdel-Monem Department of Chemistry Faculty of Education Ain-Shams University, Roxy, 11757, Cairo, Egypt.

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Dr. Wafaa R. Abdel-Monem. 2012. “. Global Journal of Science Frontier Research – B: Chemistry GJSFR-B Volume 12 (GJSFR Volume 12 Issue B5): .

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Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

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Synthesis and Antimicrobial Activity of Some New Nitrogen Heterocyclic Systems Bearing 1, 2, 4-Tiazine Moiety

Dr. Wafaa R. Abdel-Monem
Dr. Wafaa R. Abdel-Monem Department of Chemistry Faculty of Education Ain-Shams University, Roxy, 11757, Cairo, Egypt.

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