The Possible Clinical Beneficial Effects of Atorvastatin in Iraqi Patients with Systolic Heart Failure

Masar S. Baker
Masar S. Baker
Dr. Masar Samir Baker
Dr. Masar Samir Baker
Prof. Dr. Kassim Al-Shamma
Prof. Dr. Kassim Al-Shamma
Dr.Mohammed Noori Al-Dujaili
Dr.Mohammed Noori Al-Dujaili
University of Baghdad University of Baghdad

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The Possible Clinical Beneficial Effects of Atorvastatin in Iraqi Patients with Systolic Heart Failure

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Abstract

This study was designed to evaluate the therapeutic effectiveness of atorvastatin in Iraqi patients with systolic heart failure. Sixty heart failure patients were participated in this study and their ages ranged from (35-72) years. The patients were divided into three groups: patients with heart failure and normal lipid profile not receiving atorvastatin (group one), patients with heart failure and normal lipid profile receiving atorvastatin (group two), patients with heart failure and dyslipidemia receiving atorvastatin. Twenty healthy subjects were selected to be a normal group for the purpose of comparison. Several parameters of inflammation and oxidative stress (hs-CRP, TNF-α, total antioxidant status and adiponectin) as well as left ventricular ejection fraction were measured. The study duration was three months and the parameters were measured at baseline, one-half month and three months. The results showed that the serum level of hs-CRP, TNF-α and total antioxidant status were not significantly changed in group one patients, while they were significantly changed in the other two groups.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Masar S. Baker. 1970. \u201cThe Possible Clinical Beneficial Effects of Atorvastatin in Iraqi Patients with Systolic Heart Failure\u201d. Unknown Journal GJMR Volume 12 (GJMR Volume 12 Issue 10).

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v1.2

Issue date
December 3, 2012

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en
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The Possible Clinical Beneficial Effects of Atorvastatin in Iraqi Patients with Systolic Heart Failure

Dr. Masar Samir Baker
Dr. Masar Samir Baker
Prof. Dr. Kassim Al-Shamma
Prof. Dr. Kassim Al-Shamma
Dr.Mohammed Noori Al-Dujaili
Dr.Mohammed Noori Al-Dujaili

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