Synthesis, Characterization and Antimicrobial Activity of Azetidin-2-one based Phenyl Sulfonyl Pyrazoline Derivatives

Article ID

9YZQ0

Synthesis, Characterization and Antimicrobial Activity of Azetidin-2-one based Phenyl Sulfonyl Pyrazoline Derivatives

Shailesh H. Shah
Shailesh H. Shah Patel AMR Commerce & Patel JDKD Science College
Pankaj S. Patel
Pankaj S. Patel
Mitesh Prajapati
Mitesh Prajapati
Bharat Vaghari
Bharat Vaghari
Jayesh Parmar
Jayesh Parmar
DOI

Abstract

A new series of 4-(4-Chlorophenyl)-3-chloro-1-{4-[5-(Substituted phenyl)-1-(phenylsulfonyl)-4,5-dihydro-pyrazol-3-yl]phenyl}azetidin-2-one are synthesized by reacting 3-chloro-1-{4-[5-(Substituted phenyl)-4,5-dihydro-pyrazol-3-yl]phenyl}-4-(4-Chlorophenyl)azetidin-2-one with Benzene sulfonyl chloride in presence of pyridine. All these compounds were characterized by means of their IR, 1H NMR, Spectroscopic data and were tested for their antibacterial and antifungal activities by broth dilution method.

Synthesis, Characterization and Antimicrobial Activity of Azetidin-2-one based Phenyl Sulfonyl Pyrazoline Derivatives

A new series of 4-(4-Chlorophenyl)-3-chloro-1-{4-[5-(Substituted phenyl)-1-(phenylsulfonyl)-4,5-dihydro-pyrazol-3-yl]phenyl}azetidin-2-one are synthesized by reacting 3-chloro-1-{4-[5-(Substituted phenyl)-4,5-dihydro-pyrazol-3-yl]phenyl}-4-(4-Chlorophenyl)azetidin-2-one with Benzene sulfonyl chloride in presence of pyridine. All these compounds were characterized by means of their IR, 1H NMR, Spectroscopic data and were tested for their antibacterial and antifungal activities by broth dilution method.

Shailesh H. Shah
Shailesh H. Shah Patel AMR Commerce & Patel JDKD Science College
Pankaj S. Patel
Pankaj S. Patel
Mitesh Prajapati
Mitesh Prajapati
Bharat Vaghari
Bharat Vaghari
Jayesh Parmar
Jayesh Parmar

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Shailesh H. Shah. 2014. “. Global Journal of Science Frontier Research – B: Chemistry GJSFR-B Volume 14 (GJSFR Volume 14 Issue B1): .

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Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

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GJSFR Volume 14 Issue B1
Pg. 33- 38
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Synthesis, Characterization and Antimicrobial Activity of Azetidin-2-one based Phenyl Sulfonyl Pyrazoline Derivatives

Shailesh H. Shah
Shailesh H. Shah Patel AMR Commerce & Patel JDKD Science College
Pankaj S. Patel
Pankaj S. Patel
Mitesh Prajapati
Mitesh Prajapati
Bharat Vaghari
Bharat Vaghari
Jayesh Parmar
Jayesh Parmar

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