The Frequency of Incidental Thyroid Carcinoma in Patients with Graves Disease

The Frequency of Incidental Thyroid Carcinoma in Patients with Graves Disease

Aykut Soyder

Contact

Mustafa AonAbol

Contact

Serdar AzbaA

Contact

SavaA KoAak

Contact

Adnan Menderes University

The Frequency of Incidental Thyroid Carcinoma in Patients with Graves Disease

Article Fingerprint

ReserarchID

X9C9K

The Frequency of Incidental Thyroid Carcinoma in Patients with Graves Disease Banner

AI TAKEAWAY

Connecting with the Eternal Ground

Abstract

Background: The presence of hypoactive nodules in patients with Graves’ disease (GD) is an important factor in deciding on surgical treatment. Literatures are inconclusive about the increase in the risk of malignancy in cases of hypoactive nodules accompanying GD. The incidence of incidental malignancy in patients that underwent surgical treatment for GD were evaluated. Materials and Methods: This study included 108 patients that underwent thyroidectomy due to GD. Hypoactive nodules and diffuse hyperplasia were observed in 59 (54.6%) and 49 (45,4%) of the patients, respectively, during preoperative evaluation. In all 108 patients total thyroidectomy (TT) was the preferred surgical method. Results: Malignant histopathology was noted in 11 (10.2%) of the 108 patients. The thyroid nodules preoperatively observed in 59 patients were determined to be benign according to fine needle aspiration biopsy (FNAB), which also showed that 7 (11.9%) patients had incidental malignancy.

References

30 Cites in Article

Reference Format

D Feliciano (1992). Everything you wanted to know about GD.
Tapash Palit,Charles Miller,Darlene Miltenburg (2000). The Efficacy of Thyroidectomy for Graves' Disease: A Meta-analysis.
Michael Barakate,Gaurav Agarwal,Tom Reeve,Bruce Barraclough,Bruce Robinson,Leigh Delbridge (2002). Total thyroidectomy is now the preferred option for the surgical management of Graves’ disease.
S Shapiro,N Friedman,S Perzik,B Catz (1970). Incidence of thyroid carcinoma in GD.
Brown Dobyns,Glenn Sheline,Joseph Workman,Edythalena Tompkins,William Mcconahey,David Becker (1974). Malignant and Benign Neoplasms of the Thyroid in Patients Treated for Hyperthyroidism: A Report of the Cooperative Thyrotoxicosis Therapy Follow-up Study.
T Angusti,A Codegone,R Pellerito,A Favero (2000). Thyroid cancer prevalence after radioiodine treatment of hyperthyroidism.
F Pacini,R Elisei,Di Coscio,G Anelli,S Macchia,E Concetti,R (1988). Thyroid carcinoma in thyrotoxic patients treated by surgery.
Osamu Ozaki,Kunihiko Ito,Kaoru Kobayashi,Koji Toshima,Hiroyuki Iwasaki,Tohru Yashiro (1990). Thyroid carcinoma in Graves' disease.
Antonino Belfiore,Diego Russo,Riccardo Vigneri,Sebastiano Filetti (2001). Graves' disease, thyroid nodules and thyroid cancer.
N Carnell,W Valente (1988). Thyroid nodules in GD: classification, characterization, and response to treatment.
J Kraimps,Bouin-Pineaumh,De Mathonnetm,L Calan,J Ronceray,J Visset (2000). Multicentre study of thyroid nodules in patients with GD.
Anjali Mishra,Saroj Mishra,Amit Agarwal,Birendra Das,Gaurav Agarwal,Sanjay Gambhir (2001). Metastatic Differentiated Thyroid Carcinoma: ClinicopathologicalProfile and Outcome in an Iodine Deficient Area.
Robert Silver,Sareh Parangi (2004). Management of thyroid incidentalomas.
L Cantalamessa,M Baldini,Orsattia,L Meroni,Amodeiv,D Castagnone (1999). Thyroid nodules in GD and the risk of thyroid carcinoma.
Tzu-Chieh Chao,J Lin,L Jeng,M Chen (1999). Thyroid Cancer With Concurrent Hyperthyroidism.
J Gerenova,M Buysschaert,C De Burbure,C Daumerie (2003). Prevalence of thyroid cancer in Graves’ disease: a retrospective study of a cohort of 103 patients treated surgically.
E Mazzeferri (1990). Thyroid carcinoma and Graves's disease.
T Okamoto,Iiharam,T Obara (2000). Management of hyperthyroidism due to Graves' and nodular diseases.
T Terzioğlu,S Tezelman,Y Onaran,R Tanakol (1993). Concurrent hyperthyroidism and thyroid carcinoma.
Ayhan Koyuncu,Cengiz Aydin,Ömer Topçu,Oruç Gökçe,Şahande Elagöz,Hatice Dökmetaş (2011). Could total thyroidectomy become the standard treatment for Graves’ disease?.
A Brander,P Viikinkoski,J Nickels,L Kivisaari (1991). Thyroid gland: US screening in a random adult population..
R Sampson,L Woolner,R Bahn,L Kurland (1974). Occult thyroid carcinoma in Olmsted Country, Minnesota: prevalence at autopsy compared with that in Hiroshima and Nagasaki, Japan.
H Harach,Kaarle Franssila,Veli-Matti Wasenius (1986). Occult papillary carcinoma of the thyroid. A “normal” finding in finland. A systematic autopsy study.
C Hedinger,E Williams,L Sobin (1988). Histological typing of thyroid tumours.
M Bramley,B Harrison (1996). Papiller microcarcinoma of the thyroid gland.
Yoshio Kasuga,Akira Sugenoya,Shinya Kobayashi,Hiroyuki Masuda,Futoshi Iida (1990). The outcome of patients with thyroid carcinoma and graves' disease.
G Pellegriti,A Belfiore,D Giuffrida (1998). Outcome of differentiated thyroid cancer in Graves' patients.
G Sakorafas,J Giotakis,V Stafyla (2005). Papillary thyroid microcarcinoma: a surgical perspective.
L Farbota,Calandra Lawrence,A (1985). Thyroid carcinoma in GD.
R Behar,M Arganini,T Wu (1986). GD and thyroid cancer.

Download References

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Aykut Soyder. 2014. \u201cThe Frequency of Incidental Thyroid Carcinoma in Patients with Graves Disease\u201d. Unknown Journal GJMR-I Volume 14 (GJMR Volume 14 Issue I3).

More Citation Formats

Select Citation Style:

Download Citation

GJMR Volume 14 Issue I3

Explore Journals Explore Volume Read This Issue

Journal Specifications

Keywords

grave’s disease incidental thyroid cancer surgical treatment thyroid nodule

Submission ReceivedDecember 9, 2013
Peer Review Double Blind
Handling Editor
Accepted January 3, 2014
Published January 15, 2014

Version of record

v1.2

Issue date

August 29, 2014

Language

Experiance in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

View in VR

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

View in 3D

Article Matrices

Total Score: 104

Country: Turkey

Subject: Uncategorized

Authors: Aykut Soyder, Mustafa AonAbol, Serdar AzbaA, SavaA KoAak (PhD/Dr. count: 0)

View Count (all-time): 128

Total Views (Real + Logic): 4577

Total Downloads (simulated): 2366

Publish Date: 2014 08, Fri

Monthly Totals (Real + Logic):

Month 1: 29 views
Month 2: 37 views
Month 3: 52 views
Month 4: 57 views
Month 5: 43 views
Month 6: 44 views
Month 7: 26 views
Month 8: 54 views
Month 9: 34 views
Month 10: 41 views
Month 11: 49 views
Month 12: 26 views
Month 13: 35 views
Month 14: 28 views
Month 15: 33 views
Month 16: 28 views
Month 17: 36 views
Month 18: 37 views
Month 19: 41 views
Month 20: 33 views
Month 21: 48 views
Month 22: 19 views
Month 23: 36 views
Month 24: 31 views
Month 25: 27 views
Month 26: 39 views
Month 27: 26 views
Month 28: 25 views
Month 29: 24 views
Month 30: 29 views
Month 31: 47 views
Month 32: 18 views
Month 33: 31 views
Month 34: 18 views
Month 35: 28 views
Month 36: 26 views
Month 37: 18 views
Month 38: 35 views
Month 39: 48 views
Month 40: 26 views
Month 41: 28 views
Month 42: 38 views
Month 43: 40 views
Month 44: 42 views
Month 45: 20 views
Month 46: 23 views
Month 47: 44 views
Month 48: 34 views
Month 49: 33 views
Month 50: 45 views
Month 51: 21 views
Month 52: 42 views
Month 53: 32 views
Month 54: 46 views
Month 55: 30 views
Month 56: 35 views
Month 57: 44 views
Month 58: 31 views
Month 59: 37 views
Month 60: 36 views
Month 61: 17 views
Month 62: 38 views
Month 63: 21 views
Month 64: 17 views
Month 65: 28 views
Month 66: 16 views
Month 67: 41 views
Month 68: 29 views
Month 69: 25 views
Month 70: 31 views
Month 71: 40 views
Month 72: 27 views
Month 73: 19 views
Month 74: 34 views
Month 75: 15 views
Month 76: 33 views
Month 77: 39 views
Month 78: 22 views
Month 79: 43 views
Month 80: 27 views
Month 81: 40 views
Month 82: 31 views
Month 83: 29 views
Month 84: 25 views
Month 85: 21 views
Month 86: 44 views
Month 87: 43 views
Month 88: 27 views
Month 89: 31 views
Month 90: 44 views
Month 91: 39 views
Month 92: 32 views
Month 93: 29 views
Month 94: 37 views
Month 95: 38 views
Month 96: 23 views
Month 97: 39 views
Month 98: 22 views
Month 99: 26 views
Month 100: 25 views
Month 101: 42 views
Month 102: 13 views
Month 103: 34 views
Month 104: 12 views
Month 105: 44 views
Month 106: 12 views
Month 107: 31 views
Month 108: 21 views
Month 109: 35 views
Month 110: 39 views
Month 111: 39 views
Month 112: 33 views
Month 113: 39 views
Month 114: 29 views
Month 115: 23 views
Month 116: 29 views
Month 117: 35 views
Month 118: 25 views
Month 119: 24 views
Month 120: 13 views
Month 121: 32 views
Month 122: 39 views
Month 123: 27 views
Month 124: 38 views
Month 125: 22 views
Month 126: 31 views
Month 127: 27 views
Month 128: 24 views
Month 129: 25 views
Month 130: 26 views
Month 131: 42 views
Month 132: 24 views
Month 133: 31 views
Month 134: 20 views
Month 135: 31 views
Month 136: 46 views
Month 137: 34 views
Month 138: 37 views
Month 139: 29 views
Month 140: 32 views
Month 141: 38 views

Total Views: 4577

Total Downloads: 2366

2026 Trends

Our website is actively being updated, and changes may occur frequently. Please clear your browser cache if needed. For feedback or error reporting, please email [email protected]