Synthesis of 1-(2-(4-substitutedphenylamino)-imidazo[2,1-b] benzoxazol-3-yl) ethanone

Synthesis of 1-(2-(4-substitutedphenylamino)-imidazo[2,1-b] benzoxazol-3-yl) ethanone

Chalak Azimi

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Hatam Maarouf

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Halaleh Ahmadi

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Islamic Azad University, Tehran

Synthesis of 1-(2-(4-substitutedphenylamino)-imidazo[2,1-b] benzoxazol-3-yl) ethanone

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Abstract

4-acetyl-3-(4-substitutedphenylamino)-isoxazole-5(2H)-one, substituted on nitrogen with a 2-chlorobenzo[d] oxazole group, reacts with triethylamine (TEA) in ethanol under reflux conditions to provide a convenient synthesis of 1-(2-(4-substitutedphenylamino)-imidazo-[2,1-b]benzoxazol-3-yl)-ethanone.

References

23 Cites in Article

Reference Format

(, 11). )-isoxazol-5(2H)-ones (10, R: Me) This compound was prepared as described above, using the corresponding isoxazolone (9, R: Me) (61 mg, 0.27 mmol) and 2-chlorobenzoxazole (41.3 mg.
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(1018). ) (89 mg, 0.34 mmol) and 2-chlorobenzoxazole (52.1 mg.
W Feast,R Stephens (1933). 1022. Fluorocyclohexanes. Part XI. 1H,3H/2H-, 1H,2H/3H-, and 1H,2H,3H/-nonafluorocyclohexane.
Unknown Title.
(6(d,). 6 -DMSO)(δppm): 2.55.
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(null). Figure 2—figure supplement 1. 1H and 13C NMR spectra of compound 3..
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mmol) and triethylamine (0.4 mL) were refluxed in ethanol (10 mL) for 24 hours. The reaction mixture was left to cool to room tempreture and resulting precipitate was colleted to afford 1-(2-(4-nitrophenylamino)-imidazo.
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Chalak Azimi,Farhad Sepehraddin,Helal Tahazade (2013). Net Rearrangements of 4-acetyl-3-(4-substituted phenylamino)-2-(5-nitropyridin-2-yl)isoxazol-5(2H)-ones to Imidazo [1, 2-a]pyridines by Flash-Vacuum-Pyrolysis (F.V.P).
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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Chalak Azimi. 2014. \u201cSynthesis of 1-(2-(4-substitutedphenylamino)-imidazo[2,1-b] benzoxazol-3-yl) ethanone\u201d. Global Journal of Science Frontier Research - B: Chemistry GJSFR-B Volume 14 (GJSFR Volume 14 Issue B5).

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GJSFR Volume 14 Issue B5

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Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords

2chlorobenzo[d]oxazole Baseinducedrearrangements Imidazobenzoxazol isoxazolones

Submission ReceivedAugust 3, 2014
Peer Review Double Blind
Handling Editor
Accepted August 31, 2014
Published September 15, 2014

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v1.2

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October 20, 2014

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Article Matrices

Total Score: 83

Country: Iran

Subject: Global Journal of Science Frontier Research - B: Chemistry

Authors: Chalak Azimi, Hatam Maarouf, Halaleh Ahmadi (PhD/Dr. count: 0)

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