High Grade Infiltrative Urothelial Carcinoma- Sarcomatoid Variant, A Rare Entity: Case Report And Review of Literature

Manas Madan
Manas Madan
Tejinder Singh Bhasin
Tejinder Singh Bhasin
Mridu Manjari
Mridu Manjari
Manisha Sharma
Manisha Sharma
Bhawna
Bhawna
to Baba Farid University of Health Sciences

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High Grade Infiltrative Urothelial Carcinoma- Sarcomatoid Variant, A Rare Entity: Case Report And Review of Literature

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Abstract

In the urinary bladder, majority of the neoplasms are of pure epithelial origin. In contrast pure mesenchymal tumors and biphasic epithelial-mesenchymal neoplasms, although documented, rarely occur at this site Heterologous carcinosarcomas (also called metaplastic carcinomas or sarcomatoid carcinomas with heterologous differentiation) are defined as biphasic tumors made up of a varying mixture of carcinomatous and heterologous sarcomatous components with abrupt or gradual transition between one component and the other. These are rare tumors and account for approximately 0.3% of all bladder malignancies with a poor prognosis. Because of its unfavorable histopathologic nature and also its rarity, not much is known about the various treatment options in these tumors. The overall 5 year cancer specific survival rate after cystectomy is only 20.3%.

References

9 Cites in Article
  1. Laurent Perret,Pascal Chaubert,Daniel Hessler,Louis Guillou (1998). Primary heterologous carcinosarcoma (Metaplastic carcinoma) of the urinary bladder.
  2. D Atligan,B Parlaktas,N Uluocak,F Erdemir (2011). Sarcomatous carcinoma with osteosarcomatoid differentiation of the bladder with simultaneous sigmoid colon adenocarcinoma.
  3. S Paick (2009). Sarcomatoid Urothelial Carcinoma of the Renal Pelvis with Extremely Aggressive Clinical Behavior.
  4. Dmitry Baschinsky,Janny Chen,Manjunath Vadmal,Joel Lucas,Robert Bahnson,Theodore Niemann (2000). Carcinosarcoma of the Urinary Bladder—An Aggressive Tumor With Diverse Histogenesis.
  5. C Zachariadis (2011). A Case Report of Urinary Bladder Carcinosarcoma and Review of the Literature.
  6. A Beltran (1998). Carcinosarcoma and Sarcomatoid Carcinoma of the Bladder: Clinicopathological Study of 41 Cases.
  7. T Terada (2009). Urinary bladder carcinoma with triplicate differentiations into giant cell sarcomatoid carcinoma, squamous cell carcinoma, and papillary urothelial transitional cell carcinoma: a case report.
  8. M‐t Sung,M Wang,G Maclennan,J Eble,P‐h Tan,A Lopez‐beltran,R Montironi,J Harris,M Kuhar,L Cheng (2007). Histogenesis of sarcomatoid urothelial carcinoma of the urinary bladder: evidence for a common clonal origin with divergent differentiation.
  9. Doğan Atılgan,Yusuf Gençten (2013). Carcinosarcoma of the Bladder: A Case Report and Review of the Literature.

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Manas Madan. 2014. \u201cHigh Grade Infiltrative Urothelial Carcinoma- Sarcomatoid Variant, A Rare Entity: Case Report And Review of Literature\u201d. Global Journal of Medical Research - C: Microbiology & Pathology GJMR-C Volume 14 (GJMR Volume 14 Issue C7).

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Version of record

v1.2

Issue date
December 24, 2014

Language
en
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High Grade Infiltrative Urothelial Carcinoma- Sarcomatoid Variant, A Rare Entity: Case Report And Review of Literature

Manas Madan
Manas Madan
Tejinder Singh Bhasin
Tejinder Singh Bhasin
Mridu Manjari
Mridu Manjari
Manisha Sharma
Manisha Sharma <p>Baba Farid University of Health Sciences</p>
Bhawna
Bhawna

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