Comparative Study of Lipid Profile, Oxidants, Antioxidants Levels and Thyroid Hormone Status in Normal and Abnormal Pregnancy
Aim: The aim of the study is to evaluate thyroid status, Oxidative stress & lipid profile levels in abnormal and normal pregnancies. Material and Methods: The study includes 25 abnormal pregnant women, 25 normally healthy pregnant women. Ages ranged from 20 to 30 years. Thyroid status was estimated by ELISA method. For determination of oxidative stress Malandialdehyde (MDA) is estimated as oxidants by TBARS, Uric acid is estimated by pap method, cholesterol & HDL-C by CHOD-POD method, triglycerides by GPO-POD method. Results: In the present study, we observed that TSH is significantly increased compared to normal pregnancies TSH and FT4 are slightly decreased compared to normal pregnancies. In the present study cholesterol levels were increased in abnormal pregnancies compared to normal pregnancies and decrease in HDL cholesterol were observed in preeclamptic and eclamptic pregnant women.
