Study of Weekly Paclitaxel with Concurrent Radiotherapy V/S Weekly Cisplatin with Concurrent Radiotherapy in Advanced Cervix Carcinoma

Article ID

57320

Study of Weekly Paclitaxel with Concurrent Radiotherapy V/S Weekly Cisplatin with Concurrent Radiotherapy in Advanced Cervix Carcinoma

Dr. Prashant Rajendra Kumbhaj
Dr. Prashant Rajendra Kumbhaj 1: Department of Radiotherapy & Oncology SMS Medical College& Attached hospitals, Jaipur,Rajasthan India 2: Department of pathology, Government medica
Dr. Rameshwaram Sharma
Dr. Rameshwaram Sharma
Dr. Aseem Rai Bhatnagar
Dr. Aseem Rai Bhatnagar
Dr. Peeyush Kumar Saini
Dr. Peeyush Kumar Saini
DOI

Abstract

Purpose: To evaluate the Response and Efficacy of weekly paclitaxel with concurrent radiotherapy in comparison to weekly cislatin with concurrent radiotherapy in advanced cervical cancer patients. Methods: Patients coming to the department of radiotherapy S.M.S Hospital were included in the study.50 patients of advanced squamous cell carcinoma of cervix FIGO stage III &IV were selected. In the study and control group , patients were given 5 weeks of external beam radiotherapy followed by brachytherapy. External beam irradiation each of 200cGy/fr, on linear acceleretor by parallel opposed – anterior and posterior fields was given. External beam irradiation was followed by Intracavitary brachytherapy 700cGy/week for 3 weeks each with High Dose Rate Iridium 192 source. Patients received 50 Gy by External beam irradiation (200cGy/fr, total 25 Fr) and 21 Gy by Intracavitary brachytherapy (7Gy/fr, 3fr) .In control group, patients were treated by concurrent weekly cisplatin with external beam radiotherapy.In study group patients were treated by concurrent weekly paclitaxel with external beam radiotherapy.

Study of Weekly Paclitaxel with Concurrent Radiotherapy V/S Weekly Cisplatin with Concurrent Radiotherapy in Advanced Cervix Carcinoma

Purpose: To evaluate the Response and Efficacy of weekly paclitaxel with concurrent radiotherapy in comparison to weekly cislatin with concurrent radiotherapy in advanced cervical cancer patients. Methods: Patients coming to the department of radiotherapy S.M.S Hospital were included in the study.50 patients of advanced squamous cell carcinoma of cervix FIGO stage III &IV were selected. In the study and control group , patients were given 5 weeks of external beam radiotherapy followed by brachytherapy. External beam irradiation each of 200cGy/fr, on linear acceleretor by parallel opposed – anterior and posterior fields was given. External beam irradiation was followed by Intracavitary brachytherapy 700cGy/week for 3 weeks each with High Dose Rate Iridium 192 source. Patients received 50 Gy by External beam irradiation (200cGy/fr, total 25 Fr) and 21 Gy by Intracavitary brachytherapy (7Gy/fr, 3fr) .In control group, patients were treated by concurrent weekly cisplatin with external beam radiotherapy.In study group patients were treated by concurrent weekly paclitaxel with external beam radiotherapy.

Dr. Prashant Rajendra Kumbhaj
Dr. Prashant Rajendra Kumbhaj 1: Department of Radiotherapy & Oncology SMS Medical College& Attached hospitals, Jaipur,Rajasthan India 2: Department of pathology, Government medica
Dr. Rameshwaram Sharma
Dr. Rameshwaram Sharma
Dr. Aseem Rai Bhatnagar
Dr. Aseem Rai Bhatnagar
Dr. Peeyush Kumar Saini
Dr. Peeyush Kumar Saini

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Dr. Prashant Rajendra Kumbhaj. 1970. “. Global Journal of Medical Research – D: Radiology, Diagnostic GJMR-D Volume 13 (GJMR Volume 13 Issue D3): .

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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Study of Weekly Paclitaxel with Concurrent Radiotherapy V/S Weekly Cisplatin with Concurrent Radiotherapy in Advanced Cervix Carcinoma

Dr. Prashant Rajendra Kumbhaj
Dr. Prashant Rajendra Kumbhaj 1: Department of Radiotherapy & Oncology SMS Medical College& Attached hospitals, Jaipur,Rajasthan India 2: Department of pathology, Government medica
Dr. Rameshwaram Sharma
Dr. Rameshwaram Sharma
Dr. Aseem Rai Bhatnagar
Dr. Aseem Rai Bhatnagar
Dr. Peeyush Kumar Saini
Dr. Peeyush Kumar Saini

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