Research
Effect of Low Estrogen Level on Calcitriol and other Bone Related Parameters in Postmenopausal Women
Menopause is a major physiological event and is associated with metabolic changes. In order to study the changes associated with bone related parameters present study was planned. The study comprised 100 post menopausal women as study group and 100 ideal weight healthy premenopausal women as control. The blood samples were analyzed for following biochemical parameters serum calcium, phosphorus, alkaline phosphatase and calcitrol. Results revealed that the significant changes observed in calcium, phosphorus and calcitriol when compared to control.
Evaluation of Oxidative Stress and Urinary Calcium Creatinine Ratio in Pregnancy Induced Hypertension
The present study has been undertaken to evaluate oxidative stress and urinary calcium creatinine ratio in pregnancy induced hypertension. Study was carried out in M.Y. hospital and M.G.M. medical college during 2012 to 2013. Study comprised 250 subjects 125 normal pregnant women without any complications were taken as control and 125 pregnant women with PIH were taken study cases. Normal Gynaecological examination & history based informations were taken from each subject. Fasting blood sample and morning urine samples were collected from each subject and blood samples were analyzed for free radical estimations and urine sample analyzed for calcium and creatinine. Our study shows a significant change in free radical level and siginificant fall in urine calcium creatinine ratio as compared to control study concluded that PIH can be result of increased oxidative stress. In this condition change in urinary calcium creatinine ratio indicate its relation to renal system. Study conclude that by improving oxidative stress with proper antioxidant diet or therapy we can decrease or minimize the risk associated with PIH.
