Bio
Dr. Tetiana Holovko is a dedicated medical researcher and practitioner based in Kharkiv, Ukraine. She holds a doctorate from V. N. Karazin Kharkiv National University, where she also serves as a faculty member. Dr. Holovko's research focuses on the cardiovascular health and exercise tolerance of adolescents with rheumatic diseases, including systemic lupus erythematosus and juvenile idiopathic arthritis. With 19 publications and an h-index of 1, her work has been cited 10 times, highlighting ongoing contributions to pediatric rheumatology. In addition to her research, she actively contributes as a reviewer for the Global Journal of Medical Research. Her commitment to advancing medical knowledge in children's health care is evident through her affiliation with the Institute for Children and Adolescents Health Care of the National Academy of Medical Sciences of Ukraine.
Educational Journey
V. N. Karazin Kharkiv National University
Doctor
Experience
State Institution "Institute for Children and Adolescents Health Care at the National Academy of Medical Sciences of Ukraine"
0 - 0Research
Tolerance to Minimal Physical Activity in Adolescents With Systemic Lupus Erythematosus
In modern medicine, the issue of rheumatic diseases remains one of the most significant and socio-economically impactful problems due to the high rates of disability and loss of working capacity among these patients. The main cause of decreased quality of life and mortality in patients with systemic lupus erythematosus (SLE) is cardiovascular pathology, leading to the development of heart failure. An early symptom of myocardial dysfunction is the patient's loss of ability to perform routine physical activities in daily life. The aim of the study was to assess tolerance to minimal physical exertion in adolescents with systemic lupus erythematosus. A total of 46 adolescents with SLE were examined. They underwent the Six-Minute Walk Test (6MWT) with measurement of several parameters at rest and during the first minute of recovery following exertion. Results: Patients with SLE covered a shorter distance during the 6-minute period. Both before and after the Six-Minute Walk Test, elevated heart rate (HR) and respiratory rate (RR) values were recorded. This may indicate strain on the adaptive capacities of the cardiovascular and respiratory systems against the background of sympathetic activation of the autonomic nervous system, which likely leads to impaired autonomic regulation of these systems and disruption of myocardial perfusion.
