C.I. Okoro

Research

Some Observable Effects of Heat Flow in Response to Thermal Potentials at the Boundary

Article August 24, 2013

When heat flow is subject to temperature dependent thermal potential at the boundary, the associated local temperature field responds significantly, while the neighboring field is marginally influenced. This response results into effects quite intriguing. This paper examines these effects over a pure metallic plate. By considering both linear and non-linear thermal potentials induced at the edge of the plate as test cases, governed by Poisson Equation in 2- dimensions, finite element algorithm is employed to compute the temperature profiles. A control model is set-up, which admits Laplace Equation in 2-dimensions, and the outputs from the test models and the control model are examined and compared. The MATLAB results show notable effects. These results are discussed which are invaluable design factors for optimum efficiency of thermally driven systems such as in nuclear power plants, thermo-chemical plants, thermomechanical industries, lacers, solid state plasma, e.t.c. This paper, when incorporated with our previous work [9], serves as good theoretical grounds for believing the notable physical anomalies in heat transfer processes, such as the paradox of moving medium detected in the non-Fourier DPL heat conduction model [10]

A Stocastic Semi-Empirical Model for First Order Decay Pharmacokinetics

Article August 24, 2013

A first order stochastic semi-empirical model for pharmacokinetics is presented and the real response of drug concentration to vital pharmacokinetics parameters studied. By invoking Gaussian kinetics and the residual drug concentration eliminated, the probability densities and the response of concentration profiles are theoretically simulated, using empirical data based on our experience. The drug is administered for 3 days at regular time intervals of 3hr and 6hr, respectively, by refreshing the drug half-life. Results show that the amount of drug residue decreases with increasing dose, but increases with increase in ingestion time interval for corresponding dose. It is also shown that the real drug concentration increases to a threshold and decreases marginally for subsequent dose. However it is difficult to predict the response of drug concentration with changes in ingestion time interval. We recommend that for higher drug concentration the half-life be increased. Our simulation results qualitatively agree with those documented in the literatures