A Disseminated Myeloid Sarcoma Case Transformed into Leukemia

1
Habip Gedik
Habip Gedik
2
Rafet Eren
Rafet Eren
3
Fuat Ayd?nli
Fuat Ayd?nli
4
Osman Yoku?
Osman Yoku?
5
Ceyda Aslan
Ceyda Aslan
6
Cihan Gndo?an
Cihan Gndo?an
7
Mehmet Hilmi Do?u
Mehmet Hilmi Do?u
8
Elif Suyan?
Elif Suyan?
9
?ermin Alt?ndal
?ermin Alt?ndal

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Myeloid sarcoma (MS) is a tumoral mass which is derived from immature myeloid precursor cells. A 28 year old man without a medical history was diagnosed as isolated MS of testis and orchiectomy was performed. After a watch and wait approach, one year later relapse occured in the other testis without bone marrow involvement. Orchiectomy to the other testis was repeated. One year later, the patient presented to our hospital with masses at inguinal and right popliteal regions. Body 18F-FDG PET/CT showed increased FDG uptake in lymph nodes of aortocaval, paraaortic, paracaval, bilateral common iliac, right external iliac, bilateral inguinal regions with a diameter of maximum 3.7 cm and a SUVmax of 11.9; and also a heterogenous FDG uptake was observed in the muscles of posterior leg region. We performed bone marrow biopsy and aspiration resulting in no pathological infiltration. The patient was treated with induction treatment of AML, followed by consolidation with one cycle of high dose ARA-C. After the first cycle of high dose ARA-C, leucocytosis developed.

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No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

Habip Gedik. 2017. \u201cA Disseminated Myeloid Sarcoma Case Transformed into Leukemia\u201d. Global Journal of Medical Research - K: Interdisciplinary GJMR-K Volume 17 (GJMR Volume 17 Issue K3): .

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Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

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GJMR-K Classification: NLMC Code: WH 250
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v1.2

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July 5, 2017

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English

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Myeloid sarcoma (MS) is a tumoral mass which is derived from immature myeloid precursor cells. A 28 year old man without a medical history was diagnosed as isolated MS of testis and orchiectomy was performed. After a watch and wait approach, one year later relapse occured in the other testis without bone marrow involvement. Orchiectomy to the other testis was repeated. One year later, the patient presented to our hospital with masses at inguinal and right popliteal regions. Body 18F-FDG PET/CT showed increased FDG uptake in lymph nodes of aortocaval, paraaortic, paracaval, bilateral common iliac, right external iliac, bilateral inguinal regions with a diameter of maximum 3.7 cm and a SUVmax of 11.9; and also a heterogenous FDG uptake was observed in the muscles of posterior leg region. We performed bone marrow biopsy and aspiration resulting in no pathological infiltration. The patient was treated with induction treatment of AML, followed by consolidation with one cycle of high dose ARA-C. After the first cycle of high dose ARA-C, leucocytosis developed.

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A Disseminated Myeloid Sarcoma Case Transformed into Leukemia

Rafet Eren
Rafet Eren
Fuat Ayd?nli
Fuat Ayd?nli
Osman Yoku?
Osman Yoku?
Ceyda Aslan
Ceyda Aslan
Cihan Gndo?an
Cihan Gndo?an
Mehmet Hilmi Do?u
Mehmet Hilmi Do?u
Elif Suyan?
Elif Suyan?
?ermin Alt?ndal
?ermin Alt?ndal
Habip Gedik
Habip Gedik

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