A Study of the Psychotropic Activity of Extracts of Hedysarum  Alpinum L. and Garcinia Mangostana L.

A Study of the Psychotropic Activity of Extracts of Hedysarum Alpinum L. and Garcinia Mangostana L.

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PDDTMGX6U4

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A Study of the Psychotropic Activity of Extracts of Hedysarum Alpinum L. and Garcinia Mangostana L.

Fedorova Yu.S. Kemerovo State Medical University, Kemerovo, Russia;

Kulpin P.V.

Suslov N.I.

Denisova S.V

Tretyak V.M.

Merkuryeva A.G.

Beregovykh G.V.

Barkin I.M.

Lyamin E .S.

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Abstract

Introduction: The present research featured extracts of Hedysarum alpinum L. and Garcinia mangostana L. The extract of Hedysarum alpinum L. proved to have a more pronounced effect on the dopamine-induced changes in animal behavior in an active avoidance conditioning model as compared with such popular antipsychotic drug as haloperidol. Methodology: The antipsychotic effect was evaluated based on active avoidance conditioning model in a two-compartment shuttle chamber. The anti-anxiety effect was evaluated in terms of passive avoidance conditioning. The side depressive effect of the extracts was evaluated based on the behavior of the animals during the Open Field test.

A Study of the Psychotropic Activity of Extracts of Hedysarum Alpinum L. and Garcinia Mangostana L.

Authors

Fedorova Yu.S. Kemerovo State Medical University, Kemerovo, Russia;

Kulpin P.V.

Suslov N.I.

Denisova S.V

Tretyak V.M.

Merkuryeva A.G.

Beregovykh G.V.

Barkin I.M.

Lyamin E .S.

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How to Cite

Fedorova Yu.S.. 2020. “. Global Journal of Medical Research – B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 20 (GJMR Volume 20 Issue B4): .

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Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

GJMR Volume 20 Issue B4
Pg. 7- 13

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Classification

GJMR-B Classification: NLMC Code: QV 752

Submission Received December 12, 2019
Accepted January 1, 2020
Published January 15, 2020

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