A Study of the Psychotropic Activity of Extracts of Hedysarum  Alpinum L. and Garcinia Mangostana L.

The present research featured extracts of Hedysarum alpinum L. and Garcinia mangostana L. The extract of Hedysarum alpinum L. proved to have a more pronounced effect on the dopamine-induced changes in animal behavior in an active avoidance conditioning model as compared with such popular antipsychotic drug as haloperidol. Methodology: The antipsychotic effect was evaluated based on active avoidance conditioning model in a two-compartment shuttle chamber. The anti-anxiety effect was evaluated in terms of passive avoidance conditioning. The side depressive effect of the extracts was evaluated based on the behavior of the animals during the Open Field test.

References

10 Cites in Article

Reference Format

M Cherepnev,S Gracheva (1991). Threats Related to the Use of Quantum Effects in Cryptography.
D Casey (1996). Side effect profiles of new antipsychotic agents.
Wei Wang,Yu-Ying Zhao,Hong Liang,Qi Jia,Hu-Biao Chen (2006). Coumestans from Hedysarum multijugum.
Gershon Elison,A (1983). Anxiolytic Profiles.
P Jones,P Buckley,Schizophrenia (2006). Unknown Title.
C Koch (2004). A The Quest for Consciousness: A Neurobiological Approach.
Francisco López-Muñoz,Cecilio Alamo,Eduardo Cuenca,Winston Shen,Patrick Clervoy,Gabriel Rubio (2005). History of the Discovery and Clinical Introduction of Chlorpromazine.
J Quan (1998). Protective effect of Astragalus membranaceus (Fishc.) Bge. and Hedysarum polybotrys Hand.-Mazz. on experimental model of cerebral ischemia in rats // Zhonggo Zhong Yao.
Roger Walsh,Robert Cummins (1976). The open-field test: A critical review..
A Aliforenko,V Bykov,А Bykova,V Motov,K Kozhukhovskiy,V Pavlovskiy,V Khazanov,A Vengerovskii (2013). Pharmacokinetics of the bradykinin antagonist derivative 1,4-benzodiazepin-2-one in the experiment.

Download References

Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Fedorova Yu.S.. 2020. \u201cA Study of the Psychotropic Activity of Extracts of Hedysarum Alpinum L. and Garcinia Mangostana L.\u201d. Global Journal of Medical Research - B: Pharma, Drug Discovery, Toxicology & Medicine GJMR-B Volume 20 (GJMR Volume 20 Issue B4).

More Citation Formats

Select Citation Style:

Download Citation

GJMR Volume 20 Issue B4

Explore Journals Explore Volume Read This Issue

Journal Specifications

Crossref Journal DOI 10.17406/gjmra

Print ISSN 0975-5888

e-ISSN 2249-4618

Keywords

Not Found

Classification

GJMR-B Classification NLMC Code: QV 752

Submission ReceivedDecember 12, 2019
Peer Review Double Blind
Handling Editor
Accepted January 1, 2020
Published January 15, 2020

Version of record

v1.2

Issue date

May 11, 2020

Language

Experiance in AR

Explore published articles in an immersive Augmented Reality environment. Our platform converts research papers into interactive 3D books, allowing readers to view and interact with content using AR and VR compatible devices.

View in VR

Read in 3D

Your published article is automatically converted into a realistic 3D book. Flip through pages and read research papers in a more engaging and interactive format.

View in 3D

Article Matrices

Total Views: 2452

Total Downloads: 1139

2026 Trends

Our website is actively being updated, and changes may occur frequently. Please clear your browser cache if needed. For feedback or error reporting, please email [email protected]