Amino Acid Analysis and Preliminary Toxicological Evaluation of Garcinia Mangostana Seed Cake in Albino Rats

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Dr. Ibironke A. Ajayi
Dr. Ibironke A. Ajayi
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Emmanuel Ifedi
Emmanuel Ifedi
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Vivian N. Aghanu
Vivian N. Aghanu
α University of Ibadan University of Ibadan

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Amino Acid Analysis and Preliminary Toxicological Evaluation of Garcinia Mangostana Seed Cake in Albino Rats

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Abstract

The amino acid analysis and preliminary toxicological effect of Garcinia mangostana seed cake on albino rats have been investigated in order to determine its suitability as an additive in feed supplement. The proximate analysis of the seed cake showed that it had a high carbohydrate value of 71.02 ± 0.79% but low protein, moisture, fat and ash contents of 8.09 ± 0.21%, 10.42 ± 1.12%, 2.13 ± 0.13% and 1.8 ± 0.02% respectively.The seed cake also contains manganese, calcium, potassium, sodium, magnesium, iron, copper and zinc. The result of the phytochemical analysis revealed that Garcinia mangostana seed cake contains tannins, flavonoids and alkaloids. Among the seventeen amino acid determined in the defatted seed, glutamate gave the highest concentration of 10.94 g/100g. During the rat experiment which lasted for six weeks, both the control and test rats appeared to suffer no toxicological effect and weekly monitoring showed good physical appearance.

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Funding

No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

No ethics committee approval was required for this article type.

Data Availability

Not applicable for this article.

How to Cite This Article

Dr. Ibironke A. Ajayi. 1970. \u201cAmino Acid Analysis and Preliminary Toxicological Evaluation of Garcinia Mangostana Seed Cake in Albino Rats\u201d. Global Journal of Science Frontier Research - B: Chemistry GJSFR-B Volume 13 (GJSFR Volume 13 Issue B1): .

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GJSFR Volume 13 Issue B1
Pg. 17- 22
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Crossref Journal DOI 10.17406/GJSFR

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The amino acid analysis and preliminary toxicological effect of Garcinia mangostana seed cake on albino rats have been investigated in order to determine its suitability as an additive in feed supplement. The proximate analysis of the seed cake showed that it had a high carbohydrate value of 71.02 ± 0.79% but low protein, moisture, fat and ash contents of 8.09 ± 0.21%, 10.42 ± 1.12%, 2.13 ± 0.13% and 1.8 ± 0.02% respectively.The seed cake also contains manganese, calcium, potassium, sodium, magnesium, iron, copper and zinc. The result of the phytochemical analysis revealed that Garcinia mangostana seed cake contains tannins, flavonoids and alkaloids. Among the seventeen amino acid determined in the defatted seed, glutamate gave the highest concentration of 10.94 g/100g. During the rat experiment which lasted for six weeks, both the control and test rats appeared to suffer no toxicological effect and weekly monitoring showed good physical appearance.

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Amino Acid Analysis and Preliminary Toxicological Evaluation of Garcinia Mangostana Seed Cake in Albino Rats

Dr. Ibironke A. Ajayi
Dr. Ibironke A. Ajayi University of Ibadan
Emmanuel Ifedi
Emmanuel Ifedi
Vivian N. Aghanu
Vivian N. Aghanu

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