Amino Acid Analysis and Preliminary Toxicological Evaluation of Garcinia Mangostana Seed Cake in Albino Rats

Dr. Ibironke A. Ajayi

Amino Acid Analysis and Preliminary Toxicological Evaluation of Garcinia Mangostana Seed Cake in Albino Rats

Dr. Ibironke A. Ajayi * §

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University of Ibadan

Amino Acid Analysis and Preliminary Toxicological Evaluation of Garcinia Mangostana Seed Cake in Albino Rats

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Abstract

The amino acid analysis and preliminary toxicological effect of Garcinia mangostana seed cake on albino rats have been investigated in order to determine its suitability as an additive in feed supplement. The proximate analysis of the seed cake showed that it had a high carbohydrate value of 71.02 ± 0.79% but low protein, moisture, fat and ash contents of 8.09 ± 0.21%, 10.42 ± 1.12%, 2.13 ± 0.13% and 1.8 ± 0.02% respectively.The seed cake also contains manganese, calcium, potassium, sodium, magnesium, iron, copper and zinc. The result of the phytochemical analysis revealed that Garcinia mangostana seed cake contains tannins, flavonoids and alkaloids. Among the seventeen amino acid determined in the defatted seed, glutamate gave the highest concentration of 10.94 g/100g. During the rat experiment which lasted for six weeks, both the control and test rats appeared to suffer no toxicological effect and weekly monitoring showed good physical appearance.

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No external funding was declared for this work.

Conflict of Interest

The authors declare no conflict of interest.

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How to Cite This Article

Dr. Ajayi. 1970. "Amino Acid Analysis and Preliminary Toxicological Evaluation of Garcinia Mangostana Seed Cake in Albino Rats". Global Journal of Science Frontier Research, Global Journal of Science Frontier Research - B: Chemistry GJSFR-B Volume 13 (GJSFR Volume 13 Issue B1).

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GJSFR Volume 13 Issue B1

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Journal Specifications

Crossref Journal DOI 10.17406/GJSFR

Print ISSN 0975-5896

e-ISSN 2249-4626

Keywords

amino acid Garcinia mangostana Mineral element Phytochemical proximate toxicological effect

Classification

GJSFR-B Classification FOR Code: 070204

110101

Submission ReceivedDecember 8, 2012
Peer Review Double Blind
Handling Editor
Accepted January 1, 2013
Published January 16, 2013

Version of record

v1.2

Language

English

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Total Score: 152

Country: Nigeria

Subject: Global Journal of Science Frontier Research

Authors: Dr. Ibironke A. Ajayi, Emmanuel Ifedi, Vivian N. Aghanu (PhD/Dr. count: 1)

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